Evidence map›Paper›PMID 39453480›Full record

ArticleWiener klinische Wochenschrift2025

Surgical and oncological outcome after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma : A retrospective single center experience.

Catharina Müller, Michael Bergmann, Anton Stift, Thomas Bachleitner-Hofmann, Stefan Riss

Abstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catharina MüllerDepartment of Surgery, Division of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.
Michael BergmannDepartment of Surgery, Division of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.
Anton StiftDepartment of Surgery, Division of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.
Thomas Bachleitner-HofmannDepartment of Surgery, Division of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria. thomas.bachleitner-hofmann@chirurgiemitte.at.
Stefan RissDepartment of Surgery, Division of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeritoneal mesothelioma (PM) is a rare disease with various histopathological subtypes. For malignant peritoneal mesothelioma and borderline subgroups locoregional therapy with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has been implemented. The aim of our study was to retrospectively present the outcome after CRS and HIPEC for patients with different subtypes of peritoneal mesothelioma.

methodsIn total 15 patients received CRS and HIPEC due to peritoneal mesothelioma at our tertiary referral hospital between 2013 and 2022. Surgical and oncologic outcomes of 14 of those patients were retrospectively evaluated as one patient was lost to follow-up.

resultsThe cohort consisted of 9 patients with diffuse malignant peritoneal mesothelioma (64.3%), 3 patients with multicystic peritoneal mesothelioma (21.4%) and 2 patients with well-differentiated peritoneal mesothelioma (14.3%). Complete cytoreduction was possible in 85.7% (n = 12). The major complication rate was 28.6% (n = 4) and the reoperation rate was 14.3% (n = 2). Median follow-up was 55 months (standard error, SE 15.0%, 95% confidence interval, CI 25.6-84.4 months). Over this time period 64.3% (n = 9) had no evidence of disease, 21.4% (n = 3) were alive with disease and 14.3% (n = 2) died of peritoneal mesothelioma. The median recurrence-free survival of patients was 13 months (SE 13.0%, 95% CI 0.0-32.2 months). None of the patients with multicystic peritoneal mesothelioma had evidence of disease at the time of last follow-up.

conclusionPatients with peritoneal mesothelioma should receive locoregional treatment as good oncological results can be achieved with reasonable postoperative morbidity. Thus, awareness is necessary for this rare but potentially aggressive disease to offer the best medical care.

Indexed as

Cytoreduction Surgical ProceduresHyperthermia, InducedHyperthermic Intraperitoneal ChemotherapyLung NeoplasmsMesotheliomaPeritoneal NeoplasmsAdultAgedCombined Modality TherapyFemaleHumansMaleMesothelioma, MalignantMiddle AgedRetrospective StudiesSurvival RateMalignant peritoneal mesotheliomaOncologyPeritoneal mesotheliomaPeritoneal surface malignanciesSurgery

Identifiers

PMID39453480
PMCPMC12006246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.