Evidence map›Paper›PMID 39453257›Full record

ArticleTropical medicine and infectious disease2024

The Spectrum of Pathogens Associated with Infections in African Children with Severe Acute Malnutrition: A Scoping Review.

Bassey Ekeng, Olufunke Adedokun, Vivien Otu, Stella Chukwuma, Agatha Okah, Osamagbe Asemota, Ubokobong Eshiet, Usenobong Akpan, Rosa Nwagboso, Eti Ebiekpi and 2 more

Abstract readScoping Review
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bassey EkengDepartment of Medical Microbiology and Parasitology, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.ORCID 0000-0002-0509-2480
Olufunke AdedokunDepartment of Paediatrics, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.
Vivien OtuDepartment of Paediatrics, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.
Stella ChukwumaDepartment of Medical Microbiology, College of Medicine, Enugu State University of Science and Technology, Enugu 400283, Nigeria.
Agatha OkahDepartment of Paediatrics, University Hospitals Coventry and Warwickshire, NHS Trust, Coventry CV2 2DX, UK.ORCID 0009-0004-0450-0974
Osamagbe AsemotaDepartment of Paediatrics, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.ORCID 0000-0003-4405-2227
Ubokobong EshietDepartment of Paediatrics, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.
Usenobong AkpanDepartment of Paediatrics, University of Uyo Teaching Hospital, Uyo 520261, Nigeria.
Rosa NwagbosoDepartment of Family Medicine, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.
Eti EbiekpiDepartment of Community Medicine, University of Uyo Teaching Hospital, Uyo 520261, Nigeria.
Emmanuella UmorenDepartment of Paediatrics, Leeds Teaching Hospital Trust, Leeds LS1 3EX, UK.
Edet UsunDepartment of Paediatrics, University of Calabar Teaching Hospital, Calabar 540271, Nigeria.ORCID 0009-0001-3978-6501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the interplay between infections and severe acute malnutrition is critical in attaining good clinical outcomes when managing malnourished children. However, review studies describing the profile of the associated pathogens in the malnourished African paediatric population are sparse in the literature. We aimed to identify the spectrum of pathogens from studies reporting infections in severely malnourished African children, as well as the antibiotic resistance pattern and clinical outcomes. A systematic literature review of the PubMed database was conducted following PRISMA guidelines from January 2001 to June 2024. The search algorithm was ((marasmus) OR (kwashiorkor) OR (severe acute malnutrition) OR (protein energy malnutrition)) AND (Africa). For a more comprehensive retrieval, an additional search algorithm was deployed: ((HIV) OR (tuberculosis)) AND (severe acute malnutrition). We included 60 studies conducted between 2001 and 2024. Most of the studies were from East Africa (n = 45, 75%) and Southern Africa (n = 5, 8.3%). A total of 5845 pathogens were identified comprising 2007 viruses, 2275 bacteria, 1444 parasites, and 119 fungal pathogens. The predominant pathogens were HIV,

Indexed as

AfricaHIV/AIDSimmunocompromisedsevere acute malnutritiontuberculosis

Identifiers

PMID39453257
PMCPMC11510937

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.