Evidence map›Paper›PMID 39453189›Full record

ReviewToxins2024

Ultrasound-Guided Botulinum Toxin-A Injections into the Masseter Muscle for Both Medical and Aesthetic Purposes.

Marius Nicolae Popescu, Cristina Beiu, Carmen Andrada Iliescu, Andreea Racoviță, Mihai Berteanu, Mădălina Gabriela Iliescu, Ana Maria Alexandra Stănescu, Diana Sabina Radaschin, Liliana Gabriela Popa

Abstract readReview
In one paragraph

Review in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. Introduction toToxins · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marius Nicolae PopescuDepartment of Physical and Rehabilitation Medicine, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-9043-7585
Cristina BeiuDepartment of Oncologic Dermatology, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-4632-576X
Carmen Andrada IliescuClinic of Dermatology, Elias Emergency University Hospital, 011461 Bucharest, Romania.
Andreea RacovițăClinic of Dermatology, Elias Emergency University Hospital, 011461 Bucharest, Romania.ORCID 0000-0001-8868-5435
Mihai BerteanuDepartment of Physical and Rehabilitation Medicine, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-9379-4580
Mădălina Gabriela IliescuDepartment of Medical Rehabilitation, Ovidius University, 900527 Constanța, Romania.ORCID 0000-0002-8573-3160
Ana Maria Alexandra StănescuDepartment of Family Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-4807-9470
Diana Sabina RadaschinDepartment of Clinical Medical, Faculty of Medicine and Pharmacy, Dunărea de Jos University, 800385 Galați, Romania.
Liliana Gabriela PopaDepartment of Oncologic Dermatology, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increasing use of Botulinum toxin type A (BoNT-A) injections in the masseter muscles for both medical and aesthetic purposes, there is a constant need to continually enhance the efficacy of these treatments and reduce the risk of potential adverse events. This review provides an in-depth analysis of the masseter muscle's anatomical structure and essential landmarks and emphasizes the advantages of ultrasound (US) guidance in improving the precision of BoNT-A injections compared to conventional blind methods. The review is supplemented with comprehensive figures, including graphics, clinical images, and ultrasound visuals, to support the discussion. Potential complications such as paradoxical bulging, inadvertent injections into the risorius muscle or parotid gland, facial paralysis, and the risk of bone resorption are examined. Future research should aim at refining injection techniques and assessing the long-term effects of repeated treatments to ensure optimal patient care and safety.

Indexed as

Botulinum Toxins, Type AMasseter MuscleNeuromuscular AgentsUltrasonography, InterventionalHumansInjections, IntramuscularBotulinum Toxins, Type ANeuromuscular Agentsbotulinum toxin type A (BoNT-A)masseter muscle hypertrophyultrasound-guided injection

Identifiers

PMID39453189
PMCPMC11511025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.