Evidence map›Paper›PMID 39453150›Full record

ReviewToxics2024

Health Implications of Widespread Micro- and Nanoplastic Exposure: Environmental Prevalence, Mechanisms, and Biological Impact on Humans.

Olivia-Teodora Preda, Ana-Maria Vlasceanu, Cristina Veronica Andreescu, Aristidis Tsatsakis, Yaroslav Mezhuev, Carolina Negrei, Daniela Luiza Baconi

Abstract readReview
In one paragraph

Review in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olivia-Teodora PredaDepartment of Toxicology, Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 20021 Bucharest, Romania.
Ana-Maria VlasceanuDepartment of Toxicology, Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 20021 Bucharest, Romania.ORCID 0000-0002-7276-2835
Cristina Veronica AndreescuDepartment of Foreign Languages, Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 20021 Bucharest, Romania.
Aristidis TsatsakisCenter of Toxicology Science & Research, Division of Morphology, Medical School, University of Crete, Voutes Campus, 71003 Heraklion, Greece.ORCID 0000-0003-3824-2462
Yaroslav MezhuevDepartment of Biomaterials, Mendeleev University of Chemical Technology of Russia, Miusskaya sq., 9, 125047 Moscow, Russia.
Carolina NegreiDepartment of Toxicology, Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 20021 Bucharest, Romania.
Daniela Luiza BaconiDepartment of Toxicology, Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Street, Sector 2, 20021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing awareness of the potential health risks associated with microplastics' (MPs) and nanoplastics' (NPs) presence in the environment has led to a significant rise in research focused on these particles over the past few years. This review focuses on the research on MPs'/NPs' presence and spread, pathways of exposure, toxicological effects on human health and legal framework related to MP/NP challenges. Several research projects have aimed to assess their potential harm to human health, focusing on different systems and organs. After exposure (independent of the pathway), these hazards reach the blood stream and concentrate in different organs. Further, they are responsible for harmful changes, having an immediate effect (pain, inflammation, or hormone imbalance) or lead to a long-term disease (e.g., infertility, chronic obstructive pulmonary disease, or cancer). Toxicological effects have been noticed at high concentrations of MPs, specifically polystyrene, the most widespread typical MP, but only short-term effects have been mostly studied. Significant quantities of consumed MPs have been discovered to have diverse detrimental effects, posing a threat to human welfare. The exact concentrations of microplastics that are inhaled and swallowed and then build up in the human body are still not known. Further investigation is necessary to evaluate the impact of MP/NP contamination at minimal concentrations and for prolonged durations.

Indexed as

microplasticsnanoplasticspollutionpolyethylenepolypropylenepolystyrene

Identifiers

PMID39453150
PMCPMC11511527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.