Evidence map›Paper›PMID 39453149›Full record

ArticleToxics2024

Biodegradation of the Antiretroviral Tenofovir Disoproxil by a Cyanobacteria/Bacterial Culture.

Sandra Regina Silva, Gabriel Souza-Silva, Carolina Paula de Souza Moreira, Olívia Maria de Sousa Ribeiro Vasconcelos, Micheline Rosa Silveira, Francisco Antonio Rodrigues Barbosa, Sergia Maria Starling Magalhães, Marcos Paulo Gomes Mol

Abstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Remediation strategies of antiretroviral drugs in the aquatic environment: current trend and future perspectives.Water science and technology : a journal of the International Association on Water Pollution Research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandra Regina SilvaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 30510010, Brazil.
Gabriel Souza-SilvaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 30510010, Brazil.ORCID 0000-0002-3740-4346
Carolina Paula de Souza MoreiraFundação Ezequiel Dias, Departamento de Pesquisa e Desenvolvimento, Belo Horizonte 30510010, Brazil.
Olívia Maria de Sousa Ribeiro VasconcelosFundação Ezequiel Dias, Departamento de Pesquisa e Desenvolvimento, Belo Horizonte 30510010, Brazil.
Micheline Rosa SilveiraFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 30510010, Brazil.
Francisco Antonio Rodrigues BarbosaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 30510010, Brazil.ORCID 0000-0002-2026-6936
Sergia Maria Starling MagalhãesFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte 30510010, Brazil.
Marcos Paulo Gomes MolFundação Ezequiel Dias, Departamento de Pesquisa e Desenvolvimento, Belo Horizonte 30510010, Brazil.ORCID 0000-0002-2568-3579

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais NA
6 · The paper itself

Abstract

Tenofovir disoproxil fumarate (TDF) is an antiretroviral drug extensively used by people living with HIV. The TDF molecule is hydrolysed in vivo and liberates tenofovir, the active part of the molecule. Tenofovir is a very stable drug and the discharge of its residues into the environment can potentially lead to risk for aquatic species. This study evaluated the TDF biodegradation and removal by cultures of

Indexed as

by-productsdrugMicrocystis novacekiiPseudomonas pseudoalcaligenestenofovir isoproxil monoester

Identifiers

PMID39453149
PMCPMC11510927

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.