ArticleToxics2024
Experimental Investigations of Assessment of Acute Toxicity of Drilling Mud.
Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
At present, the main technological stages of oil production related to drilling operations require the use of a wide variety of drilling mud, which has a complex, multicomponent chemical composition. The drilling mud used and the resulting drilling waste must be safe for human health and the environment. The toxicity and hazard of drilling mud at this point in time remain poorly understood scientific problems and require detailing and studying in toxicological terms. The real degree of hazard and toxicity of drilling mud can only be determined by an experimental method, since its composition, which changes depending on the nature of the technological process and its degree of depletion, is not constant, which can change the toxicological properties. In an experiment conducted on adult male rats, under conditions of a single intragastric injection of drilling mud, new data were obtained regarding the parameters of its toxicity and hazard. The use of a wide variety of methods for determining lethal doses of drilling mud, including the probit analysis method, made it possible not only to substantiate the mean lethal dose of drilling mud but also other parameters of toxicity and survival of animals in the experimental groups. Features of eating behavior and body weight dynamics and the nature of the behavioral reactions revealed by the number and duration of stands and frequency and duration of grooming also indicate the presence of dose-dependent effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.