Evidence map›Paper›PMID 39453109›Full record

ArticleToxics2024

Occupational Exposures, Chronic Obstructive Pulmonary Disease and Tomographic Findings in the Spanish Population.

Eduardo Loeb, Jan-Paul Zock, Marc Miravitlles, Esther Rodríguez, Hans Kromhout, Roel Vermeulen, Juan José Soler-Cataluña, Joan B Soriano, Francisco García-Río, Pilar de Lucas and 6 more

Abstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Eduardo LoebDepartamento de Medicina, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.
Jan-Paul ZockNational Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven, The Netherlands.ORCID 0000-0002-2941-6259
Marc MiravitllesServicio de Neumología, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0002-9850-9520
Esther RodríguezDepartamento de Medicina, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.
Hans KromhoutInstitute for Risk Assessment Sciences, Utrecht University, 3584 CM Utrecht, The Netherlands.ORCID 0000-0002-4233-1890
Roel VermeulenInstitute for Risk Assessment Sciences, Utrecht University, 3584 CM Utrecht, The Netherlands.ORCID 0000-0003-4082-8163
Juan José Soler-CataluñaCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0003-1134-0783
Joan B SorianoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0001-9740-2994
Francisco García-RíoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0002-7227-2238
Pilar de LucasServicio de Neumología, Hospital General Gregorio Marañon, 28007 Madrid, Spain.ORCID 0000-0002-9377-8262
Inmaculada AlfagemeDepartamento de Medicina, Unidad de Gestión Clínica de Neumología, Hospital Universitario Virgen de Valme, Universidad de Sevilla, 41014 Sevilla, Spain.
Ciro CasanovaDepartamento de Medicina, Servicio de Neumología-Unidad de Investigación Hospital Universitario Nuestra Señora de Candelaria, CIBERES, ISCIII, Universidad de La Laguna, 38010 Santa Cruz de Tenerife, Spain.ORCID 0000-0001-7364-7508
José Rodríguez González-MoroDepartamento de Medicina, Servicio de Neumología, Hospital Universitario Vithas Madrid Arturo Soria, Universidad Europea (UE), 28043 Madrid, Spain.ORCID 0000-0002-8446-3373
Julio AncocheaCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.
Borja G CosíoCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.ORCID 0000-0002-6388-8209
Jaume Ferrer SanchoDepartamento de Medicina, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.

Funding

GlaxoSmithKline (Spain) without number
6 · The paper itself

Abstract

Self-reported occupational exposure was previously associated with COPD in the Spanish population. This study aimed to analyse the relationship between occupational exposure to various chemical and biological agents, COPD, emphysema, and the bronchial wall area, which was determined by lung computed tomography (CT) in 226 individuals with COPD and 300 individuals without COPD. Lifetime occupational exposures were assessed using the ALOHA(+) job exposure matrix, and CT and spirometry were also performed. COPD was associated with high exposure to vapours, gases, dust and fumes (VGDF) (OR 2.25 95% CI 1.19-4.22), biological dust (OR 3.01 95% CI 1.22-7.45), gases/fumes (OR 2.49 95% CI 1.20-5.17) and with exposure to various types of solvents. High exposure to gases/fumes, chlorinated solvents and metals (coefficient 8.65 95% CI 1.21-16.09, 11.91 95%CI 0.46- 23.36, 14.45 95% CI 4.42-24.49, respectively) and low exposure to aromatic solvents (coefficient 8.43 95% CI 1.16-15.70) were associated with a low 15th percentile of lung density indicating emphysema. We conclude that occupational exposure to several specific agents is associated with COPD and emphysema in the Spanish population.

Indexed as

chronic obstructive pulmonary diseasecomputed tomographyCOPDemphysemaJEMjob exposure matrixoccupational exposures

Identifiers

PMID39453109
PMCPMC11510821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.