Evidence map›Paper›PMID 39452838›Full record

ReviewNon-coding RNA2024

MicroRNA Biogenesis, Gene Regulation Mechanisms, and Availability in Foods.

Amilton S de Mello, Bradley S Ferguson, Erica L Shebs-Maurine, Francine M Giotto

Abstract readReview
In one paragraph

Review in Non-coding RNA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  12. Non-coding RNA-mediated gene regulation in Alzheimer's disease pathogenesis: molecular insights and emerging innovations.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amilton S de MelloDepartment of Agriculture, Veterinary and Rangeland Sciences, University of Nevada, Reno 1664 N. Virginia St. Mail Stop 202, Reno, NV 89557, USA.
Bradley S FergusonDepartment of Nutrition, University of Nevada, 1664 N. Virginia St. Mail Stop 202, Reno, NV 89557, USA.ORCID 0000-0003-0357-6075
Erica L Shebs-MaurineDepartment of Agriculture, Veterinary and Rangeland Sciences, University of Nevada, Reno 1664 N. Virginia St. Mail Stop 202, Reno, NV 89557, USA.
Francine M GiottoDepartment of Agriculture, Veterinary and Rangeland Sciences, University of Nevada, Reno 1664 N. Virginia St. Mail Stop 202, Reno, NV 89557, USA.ORCID 0000-0001-6091-7337

Funding

Transgenic Animal Genotyping and Phenotyping CoreP20GM130459 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Nathan Grainger · 2019 to 2026
$20.3M
NCBA Beef Checkoff 2300812NIGMS NIH HHS P20 GM130459
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small, non-coding RNAs that control gene expression by degrading or repressing mRNA translation into proteins. Research recently suggested that food-derived miRNAs are bioavailable and may be absorbed in the gastrointestinal tract (GIT). Since these small RNAs may reach the circulation and organs, possible interactions with host genes will lead to epigenetic effects that alter metabolism. Therefore, from a precision nutrition standpoint, exogenous miRNAs may be essential in modulating health status. This review summarizes the process of miRNA biogenesis, the post-translational mechanisms of gene regulation, and their bioavailability in animal- and plant-derived foods.

Indexed as

foodmicroRNAsnutrigenomics

Identifiers

PMID39452838
PMCPMC11510440

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.