Evidence map›Paper›PMID 39452722›Full record

ArticlePathogens (Basel, Switzerland)2024

Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis.

Emmanuel Oluwadare Balogun, Gideon Ibrahim Joseph, Samuel Charles Olabode, Naziru Abdulkadir Dayaso, Ammar Usman Danazumi, Rachael Bashford-Rogers, James H Mckerrow, Ghulam Jeelani, Conor R Caffrey

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emmanuel Oluwadare BalogunDepartment of Biochemistry, Ahmadu Bello University, Zaria 810001, Kaduna, Nigeria.ORCID 0000-0002-2092-0045
Gideon Ibrahim JosephDepartment of Biochemistry, Federal University of Technology, Minna PMB 65, Niger, Nigeria.ORCID 0000-0001-7195-6905
Samuel Charles OlabodeDepartment of Biochemistry, Ahmadu Bello University, Zaria 810001, Kaduna, Nigeria.
Naziru Abdulkadir DayasoDepartment of Biochemistry, Ahmadu Bello University, Zaria 810001, Kaduna, Nigeria.ORCID 0009-0003-6691-0920
Ammar Usman DanazumiDepartment of Biochemistry, Ahmadu Bello University, Zaria 810001, Kaduna, Nigeria.ORCID 0000-0003-3763-056X
Rachael Bashford-RogersDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID 0000-0002-6838-0711
James H MckerrowCenter for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, MC0657, La Jolla, CA 92093, USA.
Ghulam JeelaniDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.ORCID 0000-0003-0816-9831
Conor R CaffreyCenter for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, MC0657, La Jolla, CA 92093, USA.

Funding

Multi-target approach to rational design of novel therapeutics for human African trypanosomiasisK43TW012015 · FIC · AHMADU BELLO UNIVERSITY · PI BALOGUN, EMMANUEL OLUWADARE · 2021 to 2025
$577k
FIC NIH HHS K43 TW012015
6 · The paper itself

Abstract

Human schistosomiasis, caused by the

Indexed as

Molecular Docking SimulationSchistosomiasisVaccinesAnimalsComputational BiologyDrug DesignEpitopes, B-LymphocyteEpitopes, T-LymphocyteHumansSchistosomaSmall Molecule LibrariesVaccine DevelopmentWorkflowEpitopes, B-LymphocyteEpitopes, T-LymphocyteSmall Molecule LibrariesVaccinescathepsin proteasesdrug and vaccineimmunoinformaticsSchistosoma

Identifiers

PMID39452722
PMCPMC11509903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.