Evidence map›Paper›PMID 39452562›Full record

ArticleJournal of personalized medicine2024

Incidence of Type 1 Diabetes in Children Aged 0-14 Years in Trentino-Alto Adige Region and Determinants of Onset with Ketoacidosis.

Stefania Fanti, Denise Lazzarotto, Petra Reinstadler, Nadia Quaglia, Evelina Maines, Maria Agostina Lamberti, Vittoria Cauvin, Riccardo Pertile, Massimo Soffiati, Roberto Franceschi

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stefania FantiDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.
Denise LazzarottoOspedale di Bolzano, Azienda Sanitaria dell'Alto Adige, 39100 Bolzano, Italy.
Petra ReinstadlerOspedale di Bolzano, Azienda Sanitaria dell'Alto Adige, 39100 Bolzano, Italy.
Nadia QuagliaDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.
Evelina MainesDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.ORCID 0000-0002-0445-2974
Maria Agostina LambertiOspedale di Bolzano, Azienda Sanitaria dell'Alto Adige, 39100 Bolzano, Italy.
Vittoria CauvinDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.
Riccardo PertileDepartment of Clinical and Evaluative Epidemiology, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.ORCID 0000-0003-1455-842X
Massimo SoffiatiDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.
Roberto FranceschiDepartment of Pediatrics, Santa Chiara Hospital of Trento, Azienda Provinciale per i Servizi Sanitari della Provincia Autonoma di Trento, 38122 Trento, Italy.ORCID 0000-0002-2230-7148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the incidence and the temporal trend of type 1 diabetes (T1D) and diabetic ketoacidosis (DKA) during the period 2014-2023 in youths aged 0-14 years in the Trentino-Alto Adige region, Italy.

methodsA retrospective review of all incident cases of T1D diagnosed at the two Pediatric Diabetes Centers of Bolzano and Trento was matched with diabetes exemptions (No. 344). Demographic, clinical, and socioeconomic status (SES) data at first hospitalization were collected from subjects who agreed to participate (No. 272).

resultsThe incidence of T1D was 21.5/100,000 person/years, with a peak of 31.1 in 2021 during the COVID-19 pandemic. The mean age at the onset was 8.8 ± 3.9 years. Seventy-nine percent of the subjects were Italians, primarily residents in rural areas, and SES was equally represented. The mean incidence of DKA was 36.9%. The logistic regression analysis showed that the independent characteristics of the patients with DKA were of a younger age and displayed higher glycated hemoglobin (HbA1c) values. No relation of DKA with seasonality, ethnicity, or first-degree relative (FDR) with T1D or SES was detected.

conclusionsOur study revealed an incidence of T1D in the Trentino-Alto Adige region comparable to other areas in the North of Italy. The DKA rate negatively correlated with age; therefore, targeted prevention educational campaigns to increase awareness are needed.

Indexed as

epidemiologyincidenceketoacidosispediatricT1D

Identifiers

PMID39452562
PMCPMC11508914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.