Evidence map›Paper›PMID 39452300›Full record

ArticleJournal of cardiovascular development and disease2024

A 3D Statistical Shape Model of the Right Ventricular Outflow Tract in Pulmonary Valve Replacement Patients Post-Surgical Repair.

Liam Swanson, Raphaël Sivera, Claudio Capelli, Abdulaziz Alosaimi, Dariusz Mroczek, Christopher Z Lam, Andrew Cook, Rajiv R Chaturvedi, Silvia Schievano

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. One Anatomy, Multiple Valve Choices: Interobserver Agreement in Selecting Transcatheter Pulmonary Valve.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liam SwansonInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.ORCID 0000-0002-3573-7649
Raphaël SiveraInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.ORCID 0000-0003-1157-1514
Claudio CapelliInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.
Abdulaziz AlosaimiLabatt Family Heart Centre, Division of Cardiology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
Dariusz MroczekLabatt Family Heart Centre, Division of Cardiology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.ORCID 0009-0002-2070-7276
Christopher Z LamDepartment of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.ORCID 0000-0002-4605-5600
Andrew CookInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.ORCID 0000-0001-5079-7546
Rajiv R ChaturvediLabatt Family Heart Centre, Division of Cardiology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.ORCID 0000-0002-4474-7304
Silvia SchievanoInstitute of Cardiovascular Science, University College London, London WC1E 6BT, UK.

Funding

British Heart Foundation FS/4yPhD/F/20/34134FirstRand Foundation NANIHR Biomedical Research Centres at University College London NA
6 · The paper itself

Abstract

Assessment of the right ventricular outflow tract and pulmonary arteries (RVOT) for percutaneous pulmonary valve implantation (PPVI) uses discrete measurements (diameters and lengths) from medical images. This multi-centre study identified the 3D RVOT shape features prevalent in patients late after surgical repair of congenital heart disease (CHD). A 3D RVOT statistical shape model (SSM) was computed from 81 retrospectively selected CHD patients (14.7 ± 6.8 years) who required pulmonary valve replacement late after surgical repair. A principal component analysis identified prevalent shape features (modes) within the population which were compared with standard geometric measurements (diameter, length and surface area) and between sub-groups of diagnosis, RVOT type and dysfunction. Shape mode 1 and 2 represented RVOT size and curvature and tapering and length, respectively. Shape modes 3-5 related to branch pulmonary artery calibre, conical vs. bulbous RVOTs and RVOT curvature, respectively. Tetralogy of Fallot, transannular patch type and regurgitant RVOTs were larger and straighter while conduit and stenotic types were longer and more cylindrical than other subgroups. This SSM analysed the main 3D shape features present in a population of RVOTs, exploiting the wide 3D anatomical information provided by routine imaging. This morphological information may have implications for PPVI patient selection and device design.

Indexed as

congenital heart diseasepercutaneous pulmonary valve implantationright ventricular outflow tractstatistical shape modelling

Identifiers

PMID39452300
PMCPMC11508459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.