Evidence map›Paper›PMID 39452296›Full record

ArticleJournal of cardiovascular development and disease2024

Effect of Aerobic Exercise with Blood Flow Restriction on Postexercise Hypotension in Young Adults: The Role of Histamine Receptors.

Dongnyeuck Seo, Dae Sik Song, William Boyer, Trevor Gillum, Sean Sullivan, Nailiyah Liwanag, Iltark Yoon, Jong-Kyung Kim

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dongnyeuck SeoDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.
Dae Sik SongDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.
William BoyerDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.ORCID 0000-0001-9743-6086
Trevor GillumDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.ORCID 0000-0002-9623-2353
Sean SullivanDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.ORCID 0009-0002-2568-8852
Nailiyah LiwanagDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.
Iltark YoonDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.
Jong-Kyung KimDepartment of Kinesiology, California Baptist University, 8432 Magnolia Avenue, Riverside, CA 92504, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We tested hypothesis that aerobic exercise with blood flow restriction (BFR) induced postexercise hypotension (PEH), and the reduction in blood pressure (BP) was due to peripheral vasodilation via the histamine receptors. Ten male subjects participated in this study. The subjects were randomly assigned to walk for 10 min at 6.4 km/h, 0% grade with or without BFR after taking histamine receptor blockade. Following exercise, BP was measured at 10 min interval for 60 min. Heart rate (HR), stroke volume (SV), cardiac output (CO), mean arterial pressure (MAP), and total peripheral resistance (TPR) were evaluated. Our results indicated that MAP was significantly lowered immediately after exercise at 20 min, 30 min, and 40 min before the blockade as opposed to after the blockade. A significant reduction in diastolic BP (DBP) occurred. There were no significant differences in HR, SV, CO, and TPR between before the blockade and after the blockade. MAP was substantially decreased at 20 min, 30 min, and 40 min before the blockade compared to resting (-3.2 ± 2.2, -3.3 ± 2.8, and -2.9 ± 2.5, respectively) while increasing MAP after the blockade. The current study demonstrated that low-intensity aerobic exercise with BFR lowered MAP via histamine receptor-induced peripheral vasodilation. In conclusion, BFR exercise training using short periods and low intensity would be greatly beneficial as a potential treatment to lower BP.

Indexed as

blood flow restrictioncardiac outputhistamine receptormean arterial pressuretotal peripheral resistance

Identifiers

PMID39452296
PMCPMC11508508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.