Evidence map›Paper›PMID 39452255›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Goondapyrones A-J: Polyketide α and γ Pyrone Anthelmintics from an Australian Soil-Derived

Shengbin Jin, David F Bruhn, Cynthia T Childs, Erica Burkman, Yovany Moreno, Angela A Salim, Zeinab G Khalil, Robert J Capon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shengbin JinInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-8108-4626
David F BruhnBoehringer Ingelheim Animal Health, USA Inc., 1730 Olympic Drive, Athens, GA 30601, USA.
Cynthia T ChildsBoehringer Ingelheim Animal Health, USA Inc., 1730 Olympic Drive, Athens, GA 30601, USA.
Erica BurkmanBoehringer Ingelheim Animal Health, USA Inc., 1730 Olympic Drive, Athens, GA 30601, USA.
Yovany MorenoBoehringer Ingelheim Animal Health, USA Inc., 1730 Olympic Drive, Athens, GA 30601, USA.
Angela A SalimInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-8177-5689
Zeinab G KhalilInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-9285-1720
Robert J CaponInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-8341-7754

Funding

Australian Research Council FT230100468Australian Research Council LE210100148Australian Research Council LE230100128Australian Research Council LP190100083
6 · The paper itself

Abstract

An investigation of ×19 soil samples collected under the auspices of the Australian citizen science initiative, Soils for Science, returned ×559 chemically dereplicated microbial isolates, of which ×54 exhibited noteworthy anthelmintic activity against either the heartworm

Indexed as

anthelminticcitizen scienceDirofilaria immitisHaemonchus contortusmicrobial natural productpolyketidepyronesSoils for ScienceStreptomyces

Identifiers

PMID39452255
PMCPMC11505385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.