Evidence map›Paper›PMID 39451738›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers.

Ünal Metin Tokat, Ashkan Adibi, Esranur Aydın, Eylül Özgü, Şevval Nur Bilgiç, Onur Tutar, Merve Özbek Doğançay, İrem Demiray, Mutlu Demiray

Abstract readCase Reports
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Integrated Transcriptomic Analysis ofInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ünal Metin TokatMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.
Ashkan AdibiMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.ORCID 0000-0002-0505-1558
Esranur AydınMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.ORCID 0000-0001-7850-0177
Eylül ÖzgüMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.
Şevval Nur BilgiçMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.ORCID 0000-0002-9574-1471
Onur TutarDepartment of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University, 34098 Istanbul, Türkiye.
Merve Özbek DoğançayYedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, 34020 Istanbul, Türkiye.
İrem DemirayDepartment of Molecular Biology and Genetics, Koc University, 34450 Istanbul, Türkiye.
Mutlu DemirayMedicana Health Group, Precision Oncology Center, 34750 Istanbul, Türkiye.ORCID 0000-0003-2501-3097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is currently no effective treatment strategy for recurrent/metastatic adenoid cystic carcinoma (R/M ACC). Furthermore, recent single-agent and combination immunotherapy trials have failed in unselected ACC cohorts, unlike non-ACC salivary gland cancers. Genomic profiling revealed no actionable targets but

Indexed as

Biomarkers, TumorCarcinoma, Adenoid CysticImmunotherapyPrecision MedicineFemaleHumansLung NeoplasmsMaleMiddle AgedBiomarkers, Tumoradenoid cystic carcinoma (ACC)frameshift mutationimmune checkpoint inhibitor (ICI)integrative therapiespersonalized immunotherapyprecision oncologysplice site mutation

Identifiers

PMID39451738
PMCPMC11505630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.