Evidence map›Paper›PMID 39451651›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Baseline Choroidal Blood Flow Imbalance as a Predictive Factor for Macular Edema Recurrence Secondary to Branch Retinal Vein Occlusion.

Ryuya Hashimoto, Kenichiro Aso, Keisuke Yata, Naoki Fujioka, Kazufumi Tanaka, Serika Moriyama, Asato Hirota, Juri Kawamura, Takatoshi Maeno

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Laser speckle flowgraphy (LSFG) in retinal vein occlusion and central serous chorioretinopathy: a systematic review of the recent literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Early macular choroidal hemodynamic changes after faricimab loading in treatment-naïve diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryuya HashimotoDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Kenichiro AsoDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Keisuke YataDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.ORCID 0009-0006-9227-590X
Naoki FujiokaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Kazufumi TanakaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Serika MoriyamaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Asato HirotaDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Juri KawamuraDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.
Takatoshi MaenoDepartment of Ophthalmology, Toho University Sakura Medical Center, 564-1, Shimoshizu, Sakura 285-8741, Japan.ORCID 0000-0002-7241-4726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo evaluate the roles of choroidal blood flow (CBF) and choroidal thickness (CT) as predictors of macular edema recurrence in patients with treatment-naive non-ischemic branch retinal vein occlusion (BRVO) after intravitreal ranibizumab (IVR) injection.

methodsSixteen eyes from sixteen patients with treatment-naive non-ischemic BRVO treated with IVR, once initially and then as needed, were included in the study. CBF and CT in the subfovea, occlusive, and non-occlusive regions were measured via laser speckle flowgraphy and enhanced depth imaging optical coherence tomography over 12 months.

resultsBaseline CT was significantly greater in the occlusive region (335 ± 72.1 µm) than in the non-occlusive region (274 ± 36.7 µm,

conclusionsBaseline CBF imbalance in eyes with treatment-naive BRVO may indicate the recurrence of macular edema after ranibizumab therapy.

Indexed as

anti-VEGF drugsbranch retinal vein occlusionchoroidal blood flowchoroidal thicknesslaser speckle flowgraphymacular edema

Identifiers

PMID39451651
PMCPMC11507006

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.