Evidence map›Paper›PMID 39451524›Full record

ArticleCurrent issues in molecular biology2024

Exploring miRNA Biomarkers in Major Depressive Disorder: A Molecular Medicine Perspective.

Cătălin Prodan-Bărbulescu, Laura Andreea Ghenciu, Edward Şeclăman, Georgeta Cristiana Bujor, Virgil Enătescu, Alexandra-Ioana Danila, Ecaterina Dăescu, Luminioara Maria Rosu, Ionuţ Flaviu Faur, Paul Tuţac and 3 more

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cătălin Prodan-BărbulescuFaculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0003-4348-5469
Laura Andreea GhenciuFaculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-5326-5438
Edward ŞeclămanDepartment IV-Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timișoara, 2nd Eftimie Murgu Square, 300041 Timișoara, Romania.
Georgeta Cristiana BujorDepartment IV-Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timișoara, 2nd Eftimie Murgu Square, 300041 Timișoara, Romania.
Virgil EnătescuFaculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0003-0136-1142
Alexandra-Ioana DanilaDepartment I-Discipline of Anatomy and Embryology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timișoara, Romania.ORCID 0009-0000-9118-9133
Ecaterina DăescuDepartment I-Discipline of Anatomy and Embryology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timișoara, Romania.
Luminioara Maria RosuDepartment I-Discipline of Anatomy and Embryology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timișoara, Romania.
Ionuţ Flaviu FaurIInd Surgery Clinic, Timisoara Emergency County Hospital, 300723 Timișoara, Romania.ORCID 0000-0001-6451-7461
Paul TuţacDoctoral School, Department of General Medicine, University of Medicine and Pharmacy Victor Babeş Timisoara, 300041 Timișoara, Romania.
Norberth-Istvan VargaDoctoral School, Department of General Medicine, University of Medicine and Pharmacy Victor Babeş Timisoara, 300041 Timișoara, Romania.ORCID 0009-0002-0320-6904
Tanasescu SoniaDepartment of Pediatrics, "Victor Babes" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Ciprian DuțăFaculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy Timisoara, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depressive disorder (MDD) is a complex mental health condition with a multifaceted and incompletely elucidated pathophysiology. MicroRNAs (miRNAs) have emerged as potential biomarkers due to their role in gene regulation and the observed dysregulation in MDD. The aim of this study is to detect the presence of specific molecular diagnostic biomarkers in major depressive disorder. This cross-sectional study analyzed plasma miRNA expression in ten MDD patients and eight healthy controls using real-time PCR. Differentially expressed miRNAs were identified using independent

Indexed as

depressionmajor depressive disordermiRNAmiRNA dysregulation

Identifiers

PMID39451524
PMCPMC11506240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.