Evidence map›Paper›PMID 39451492›Full record

ArticleHealthcare (Basel, Switzerland)2024

Pain Management in Knee Osteoarthritis: Insights from an Exploratory Online Survey of Italian Patients and Physicians.

Giovanni Iolascon, Alberto Migliore, Giovanna Beretta, Andrea Bernetti, Roberto Bortolotti, Antonella Celano, Antonino Giarratano, Franco Marinangeli, Alberto Momoli, Gian Domenico Sebastiani and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721208 (Development of a Mobile APP to Promote Physical Activity in Individuals With Knee Osteoarthritis), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721208 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Development of a Mobile APP to Promote Physical Activity in Individuals With Knee Osteoarthritis: a "Move for Knee" Study Protocol

TypeinterventionalSponsorUniversity of Campania Luigi VanvitelliRan2025 to 2026Enrolled150ConditionsKnee OsteoarthristisArmsuse the "Move for Knee" APP
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. 2050: An Arthroplasty Odyssey.Healthcare (Basel, Switzerland) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giovanni IolasconDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-0976-925X
Alberto MiglioreRheumatology Unit, San Pietro Fatebenefratelli Hospital, 00189 Rome, Italy.ORCID 0000-0002-3397-6478
Giovanna BerettaUnit of Rehabilitation Medicine and Neurorehabilitation, Department of Neuroscience, ASST Niguarda Hospital, 20162 Milan, Italy.
Andrea BernettiDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-0204-9831
Roberto BortolottiUnit of Rheumatology, Santa Chiara Regional Hospital, Azienda Provinciale Servizi Sanitari, 38122 Trento, Italy.ORCID 0000-0002-5728-0774
Antonella CelanoItalian National Association People with Rheumatological and Rare Diseases, APMARR Aps, 73100 Lecce, Italy.
Antonino GiarratanoDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, 90127 Palermo, Italy.
Franco MarinangeliDepartment of Anesthesiology, Intensive Care and Pain Treatment, University of L'Aquila, 67100 L'Aquila, Italy.
Alberto MomoliUnit of Trauma and Orthopaedic, San Bortolo Hospital, 36100 Vicenza, Italy.
Gian Domenico SebastianiRheumatology Unit, Azienda Ospedaliera San Camillo-Forlanini, 00152 Rome, Italy.ORCID 0000-0003-2969-6649
Andrea TomasiniItalian National Association People with Rheumatological and Rare Diseases, APMARR Aps, 73100 Lecce, Italy.
Silvia TonoloANMAR Onlus (Associazione Nazionale Malati Reumatici), 00145 Rome, Italy.
Fabiana MadottoDepartment of Anesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0002-8829-9160
Alberto Di MartinoFirst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-0716-4951
Silvia NatoliDepartment of Clinical-Surgical Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3758-5375

Funding

Grunenthal Italia srl, SERF Not applicable
6 · The paper itself

Abstract

backgroundIn Italy, knee osteoarthritis (KOA) accounts for over 5 million prevalent cases and requires long-term multidisciplinary management. The most frequent KOA symptom is pain. The aim of the survey is to provide a national overview of the current management of moderate-to-severe pain associated with KOA from both clinicians' and patients' perspectives.

methodsAn exploratory qualitative survey was conducted in Italy between July and October 2023. The survey participants were members of four national scientific societies and two patient associations who were invited to participate via email and given an online questionnaire. Questions included a mix of single and multiple responses and scalar items.

resultsIn total, 1473 clinicians and 150 patients with KOA completed the questionnaire. Patients rated knee pain as both the most burdensome symptom and the most frequent reason for treatment dissatisfaction and seeking consultation. One in two patients declared that they were unsatisfied/little satisfied with the current prescribed analgesic treatments. The clinicians surveyed preferentially prescribed intra-articular hyaluronic acid, oral non-steroidal anti-inflammatory drugs/paracetamol, non-pharmacological intervention, and intra-articular corticosteroids. The clinicians' selection of analgesic therapy often failed to adequately meet patients' expectations for pain relief.

conclusionsOur findings highlight the current unmet needs of patients with KOA in Italy and call for new approaches to effectively optimize the management of KOA-associated pain.

Indexed as

kneeosteoarthritisosteoarthritis managementpainpatient perspectivequalitative research

Identifiers

PMID39451492
PMCPMC11507079

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.