Evidence map›Paper›PMID 39451389›Full record

ArticleBioengineering (Basel, Switzerland)2024

ARISE-The Accuracy Evaluation of a Patient-Specific 3D-Printed Biopsy System Based on MRI Data: A Cadaveric Study.

Robert Möbius, Dirk Winkler, Fabian Kropla, Marcel Müller, Sebastian Scholz, Erdem Güresir, Ronny Grunert

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert MöbiusFaculty of Medicine, University Clinic of Leipzig, 04103 Leipzig, Germany.
Dirk WinklerFaculty of Medicine, University Clinic of Leipzig, 04103 Leipzig, Germany.
Fabian KroplaFaculty of Medicine, University Clinic of Leipzig, 04103 Leipzig, Germany.
Marcel MüllerFraunhofer Institute for Machine Tools and Forming Technology, 02763 Zittau, Germany.ORCID 0000-0003-0248-3029
Sebastian ScholzFraunhofer Institute for Machine Tools and Forming Technology, 02763 Zittau, Germany.
Erdem GüresirFaculty of Medicine, University Clinic of Leipzig, 04103 Leipzig, Germany.ORCID 0000-0001-8319-0847
Ronny GrunertFaculty of Medicine, University Clinic of Leipzig, 04103 Leipzig, Germany.

Funding

Federal Ministry for Economic Affairs and Climate Action 03EFMSN141
6 · The paper itself

Abstract

backgroundBrain biopsy is required for the accurate specification and further diagnosis of intracranial findings. The conventional stereotactic frames are used clinically for biopsies and offer the highest possible precision. Unfortunately, they come with some insurmountable technical and logistical limitations. The aim of the present work is to determine the clinical precision in the needle biopsy of the human brain using a new patient-specific stereotactic navigation device based on 3D printing.

methodsMRI data sets of human cadaver heads were used to plan 32 intracranial virtual biopsy targets located in different brain regions. Based on these data, 16 individualized stereotactic frames were 3D-printed. After the intraoperative application of the stereotactic device to the cadaver's head, the actual needle position was verified by postoperative CT.

resultsThirty-two brain areas were successfully biopsied. The target point accuracy was 1.05 ± 0.63 mm, which represents the difference between the planned and real target points. The largest target point deviation was in the coronal plane at 0.60 mm; the smallest was in the transverse plane (0.45 mm).

conclusionsThree-dimensional-printed, personalized stereotactic frames or platforms are an alternative to the commonly used frame-based and frameless stereotactic systems. They are particularly advantageous in terms of accuracy, reduced medical imaging, and significantly simplified intraoperative handling.

Indexed as

3D printingcerebral biopsyintracranial lesionstereotaxy

Identifiers

PMID39451389
PMCPMC11505023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.