Evidence map›Paper›PMID 39451363›Full record

ArticleBioengineering (Basel, Switzerland)2024

De-Epithelization of the Human Amniotic Membrane Using a System Involving Ozonated Water and Ultrasound.

Francisco Dimitre Rodrigo Pereira Santos, Bianca Akemi Kawata, Tatiana Regina de Oliveira Heinzelmann, Marcia Guelma Santos Belfort, Maycon Crispim de Oliveira Carvalho, Sílvia Móbille Awoyama, João Gomes de Oliveira Neto, Carlos José de Lima, Adriana Barrinha Fernandes

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francisco Dimitre Rodrigo Pereira SantosPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.ORCID 0000-0003-3036-7631
Bianca Akemi KawataCoordination of Research and Technological Development from Instituto Nacional de Pesquisas Espaciais (COPDT/INPE), São José dos Campos 12201-970, São Paulo, Brazil.
Tatiana Regina de Oliveira HeinzelmannPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.ORCID 0009-0007-4126-8571
Marcia Guelma Santos BelfortPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.
Maycon Crispim de Oliveira CarvalhoPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.ORCID 0000-0001-9282-2068
Sílvia Móbille AwoyamaCentro de Inovação, Tecnologia e Educação (CITÉ), São José dos Campos 12247-004, São Paulo, Brazil.
João Gomes de Oliveira NetoPostgraduate Program in Materials Science, Universidade Federal do Maranhã (UFMA), Imperatriz 65915-060, Maranhão, Brazil.
Carlos José de LimaPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.ORCID 0000-0001-6736-2100
Adriana Barrinha FernandesPostgraduate Program in Biomedical Engineering, Biomedical Engineering Institute, Universidade Anhembi Morumbi (UAM), São José dos Campos 12247-004, São Paulo, Brazil.ORCID 0000-0003-2965-1299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate whether a system involving ozonated water and ultrasound causes de-epithelization of the human amniotic membrane (HAM). The experiment protocol was carried out in four stages. Stage I was carried out to determine the duration of the experiment. Stage II comprised the first experiment, involving four groups of samples studied in triplicate: control/natural (IN), processed with ultrasound in a liquid medium (US), processed with ozonated water (O3), and processed with ozonated water combined with ultrasound (US_O3). Stage III was performed to confirm the results, following the same steps present in Stage II. Stage IV involved the use of oxygen to confirm the hypothesis. Histological analysis was carried out to verify whether the effects of O

Indexed as

amnionbiomaterialsde-epithelizationhuman amniotic membraneozonetissue engineeringultrasound

Identifiers

PMID39451363
PMCPMC11504975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.