Evidence map›Paper›PMID 39451353›Full record

ArticleBioengineering (Basel, Switzerland)2024

Three-Dimensional Analysis of Vocal Fold Oscillations: Correlating Superior and Medial Surface Dynamics Using Ex Vivo Human Hemilarynges.

Reinhard Veltrup, Susanne Angerer, Elena Gessner, Friederike Matheis, Emily Sümmerer, Jann-Ole Henningson, Michael Döllinger, Marion Semmler

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reinhard VeltrupUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Susanne AngererUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Elena GessnerUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Friederike MatheisUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Emily SümmererUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.
Jann-Ole HenningsonDepartment of Computer Science, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Michael DöllingerUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0003-2717-4820
Marion SemmlerUniversity Hospital Erlangen, Medical School, Division of Phoniatrics and Pediatric Audiology, Department of Otorhinolaryngology Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.

Funding

Deutsche Forschungsgemeinschaft (DFG) 1247/16-1 (awarded to Michael Döllinger) under Project Number 448240908.
6 · The paper itself

Abstract

The primary acoustic signal of the voice is generated by the complex oscillation of the vocal folds (VFs), whereby physicians can barely examine the medial VF surface due to its anatomical inaccessibility. In this study, we investigated possibilities to infer medial surface dynamics by analyzing correlations in the oscillatory behavior of the superior and medial VF surfaces of four human hemilarynges, each in 24 different combinations of flow rate, VF adduction, and elongation. The two surfaces were recorded synchronously during sustained phonation using two high-speed camera setups and were subsequently 3D-reconstructed. The 3D surface parameters of mean and maximum velocities and displacements and general phonation parameters were calculated. The VF oscillations were also analyzed using empirical eigenfunctions (EEFs) and mucosal wave propagation, calculated from medial surface trajectories. Strong linear correlations were found between the 3D parameters of the superior and medial VF surfaces, ranging from 0.8 to 0.95. The linear regressions showed similar values for the maximum velocities at all hemilarynges (0.69-0.9), indicating the most promising parameter for predicting the medial surface. Since excessive VF velocities are suspected to cause phono-trauma and VF polyps, this parameter could provide added value to laryngeal diagnostics in the future.

Indexed as

3D laryngoscopyempirical eigenfunctionshemilarynxhigh-speed imaginglaryngeal modelingmucosal wave propagationvocal folds

Identifiers

PMID39451353
PMCPMC11505270

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