Evidence map›Paper›PMID 39451343›Full record

ArticleBioengineering (Basel, Switzerland)2024

Influence of Contact Lens Parameters on Cornea: Biomechanical Analysis.

Darshan Ramasubramanian, José Luis Hernández-Verdejo, José Manuel López-Alonso

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Darshan RamasubramanianFaculty of Optics and Optometry, Complutense University of Madrid, Arcos de Jalón 118, 28037 Madrid, Spain.ORCID 0009-0006-0975-5874
José Luis Hernández-VerdejoFaculty of Optics and Optometry, Complutense University of Madrid, Arcos de Jalón 118, 28037 Madrid, Spain.ORCID 0000-0002-6418-4086
José Manuel López-AlonsoFaculty of Optics and Optometry, Complutense University of Madrid, Arcos de Jalón 118, 28037 Madrid, Spain.

Funding

European Union Horizon 2020 956274
6 · The paper itself

Abstract

This study presents a finite element analysis to model ocular biomechanics and the interactions between the human eye and contact lenses in the closed-eye condition. The closed-eye state, where the eyelids are fully shut, presents challenges for experimental measurements due to the invasive nature of accessing and analysing the contact lens and corneal interface, making simulation tools valuable for accurate characterisation. The primary objective of this study was to examine how CLs fold and twist and their impact on the cornea when the eye is closed. The secondary aim of this study was to assess how crucial contact lens parameters (Young's modulus, base curve, and diameter) influence corneal stress distribution and the overall fit of the lens on the eye. The findings show that increasing Young's modulus significantly reduces corneal stress and promotes uniform stress distribution, making it the most influential factor for wearer comfort and safety. While base curve and diameter variations primarily affect contact area, their impact on stress distribution is minimal. This research provides insights for improving contact lens design and enhancing safety for contact lens wearers.

Indexed as

contact lens designfinite element analysisocular biomechanicswearer comfort

Identifiers

PMID39451343
PMCPMC11505363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.