Evidence map›Paper›PMID 39451308›Full record

ArticleGels (Basel, Switzerland)2024

Tuning Antioxidant Function through Dynamic Design of Chitosan-Based Hydrogels.

Manuela Maria Iftime, Gabriela Liliana Ailiesei, Daniela Ailincai

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manuela Maria Iftime"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Gabriela Liliana Ailiesei"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487 Iasi, Romania.ORCID 0000-0001-5972-4562
Daniela Ailincai"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487 Iasi, Romania.

Funding

ICUB Fellowship for Young Researches (Daniela Ailincai, Contract no. 7414/September 2023) 7414/September 2023
6 · The paper itself

Abstract

Dynamic chitosan-based hydrogels with enhanced antioxidant activity were synthesized through the formation of reversible imine linkages with 5-methoxy-salicylaldehyde. These hydrogels exhibited a porous structure and swelling capacity, influenced by the crosslinking degree, as confirmed by SEM and POM analysis. The dynamic nature of the imine bonds was characterized through NMR, swelling studies in various media, and aldehyde release measurements. The hydrogels demonstrated significantly improved antioxidant activity compared to unmodified chitosan, as evaluated by the DPPH method. This research highlights the potential of developing pH-responsive chitosan-based hydrogels for a wide range of biomedical applications.

Indexed as

antioxidant propertieschitosandynamic behaviorhydrogelsimine

Identifiers

PMID39451308
PMCPMC11507920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.