Evidence map›Paper›PMID 39451256›Full record

ReviewCells2024

Apolipoprotein-L1 (APOL1): From Sleeping Sickness to Kidney Disease.

Etienne Pays

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Apolipoproteins L involvement in immunity.Journal of human immunity · 2026
    Review
  2. Article
  3. HomozygousRenal failure · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Etienne PaysLaboratory of Molecular Parasitology, Institut de Biologie et de Médecine Moléculaires (IBMM), Université Libre de Bruxelles, 6041 Gosselies, Belgium.ORCID 0000-0002-5776-5640

Funding

European Research Council 669007-APOLs
6 · The paper itself

Abstract

Apolipoprotein-L1 (APOL1) is a membrane-interacting protein induced by inflammation, which confers human resistance to infection by African trypanosomes. APOL1 kills

Indexed as

Apolipoprotein L1Kidney DiseasesTrypanosomiasis, AfricanAnimalsHumansPodocytesTrypanosoma brucei bruceiAPOL1 protein, humanApolipoprotein L1APOL1 risk variantsapoptosisARF1cation channelscholesterol microdomainschronic kidney diseaseINF-I inflammationmembrane dynamicsmitochondrion fissionmitophagyN264K variantNCS1PI4KBsleeping sickness

Identifiers

PMID39451256
PMCPMC11506758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.