Evidence map›Paper›PMID 39451254›Full record

ArticleCells2024

Excess Potassium Promotes Autophagy to Maintain the Immunosuppressive Capacity of Myeloid-Derived Suppressor Cells Independent of Arginase 1.

Ramesh Thylur Puttalingaiah, Matthew J Dean, Liqin Zheng, Phaethon Philbrook, Dorota Wyczechowska, Timothy Kayes, Luis Del Valle, Denise Danos, Maria Dulfary Sanchez-Pino

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ramesh Thylur PuttalingaiahStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0001-8935-6780
Matthew J DeanStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Liqin ZhengStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Phaethon PhilbrookStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-4927-8092
Dorota WyczechowskaStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-8940-6861
Timothy KayesStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Luis Del ValleStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0003-3894-9206
Denise DanosStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
Maria Dulfary Sanchez-PinoStanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0001-5271-9840

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Understanding and Addressing Cancer Health Disparities in LouisianaP20CA233374 · NCI · LSU HEALTH SCIENCES CENTER · PI MIELE, LUCIO, OCHOA, AUGUSTO C. · 2018 to 2020
$2.9M
Louisiana Clinical and Translational Science Center U54-GM104940NCI NIH HHS P20 CA233374NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Potassium ions (K

Indexed as

ArginaseAutophagyMyeloid-Derived Suppressor CellsNitric Oxide Synthase Type IIPotassiumAnimalsCCAAT-Enhancer-Binding Protein-betaCell ProliferationMiceMice, Inbred C57BLMitochondriaT-LymphocytesArg1 protein, mouseArginaseCCAAT-Enhancer-Binding Protein-betaNitric Oxide Synthase Type IIPotassiumarginase IautophagyK+ ions, immunosuppressionMDSCspotassium

Identifiers

PMID39451254
PMCPMC11505641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.