Evidence map›Paper›PMID 39451025›Full record

Trial reportPediatric pulmonology2025

Objective detection of wheeze at home by parents through a digital device: usage patterns and relationship with SABA administration.

Yen Hoang Do, Wim van Aalderen, Ellen Dellbrügger, Claude Grenzbach, Jonathan Grigg, Ulrike Grittner, Eric Haarman, Camilo José Hernandez Toro, Bulent Karadag, Siri Roßberg and 5 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yen Hoang DoDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Wim van AalderenDepartment of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Ellen DellbrüggerPediatric Pulmonologist, Berlin, Germany.
Claude GrenzbachPediatric Pulmonologist, Berlin, Germany.
Jonathan GriggCentre for Genomics and Child Health, Blizard Institute, Queen Mary University of London, London, UK.
Ulrike GrittnerInstitute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Eric HaarmanDepartment of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Camilo José Hernandez ToroDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Bulent KaradagDivision of Pediatric Pulmonology, Marmara University, Istanbul, Turkey.
Siri RoßbergPediatric Pulmonologist, Berlin, Germany.
Tina-Maria WeichertPediatric Pulmonologist, Berlin, Germany.
Abigail WhitehouseCentre for Genomics and Child Health, Blizard Institute, Queen Mary University of London, London, UK.
Antonio PizzulliPediatric Pulmonologist, Berlin, Germany.
Stephanie DramburgDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
Paolo Maria MatricardiDepartment of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-5485-0324

Funding

Omron Healthcare Jp.
6 · The paper itself

Abstract

introductionWheezing is an important indicator of exacerbated respiratory symptoms in early childhood and must be monitored to regulate pharmacological therapy. However, parents' subjective perception of wheezing in their children is not always precise. We investigated the objective identification of children's wheezing by parents using a digital wheeze detector (WheezeScan

methodsWe conducted a secondary nested analysis of data from the intervention arm of a multi-center randomized controlled trial completed in 2021-2022 in Berlin (Germany), London (United Kingdom), and Istanbul (Turkey). Children aged 4 to 84 months with doctor's diagnosed wheezing (GINA step 1 or 2) were included. Using an electronic diary (Wheeze-Monitor

resultsEighty-one/87 families completed the intervention arm of the study. WheezeScan

conclusionDaily use of a digital WheezeScan

Indexed as

ParentsRespiratory SoundsAdrenergic beta-2 Receptor AgonistsAsthmaChildChild, PreschoolFemaleHumansInfantMaleQuality of LifeSurveys and QuestionnairesAdrenergic beta-2 Receptor Agonistschildhooddigital healthpre‐school wheezingself‐managementwheeze detector

Identifiers

PMID39451025
PMCPMC11715141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.