Evidence map›Paper›PMID 39450764›Full record

ArticleJournal of the American Chemical Society2024

Redox-Neutral, Iron-Mediated Directed C-H Activation: General Principles and Mechanistic Insights.

Tianyi Zhang, William G Whitehurst, Matthew V Pecoraro, Junho Kim, Stefan G Koenig, Paul J Chirik

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Iron(III)-catalyzed activation of C(spNature communications · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianyi ZhangDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-8289-3102
William G WhitehurstDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-9789-1265
Matthew V PecoraroDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0003-2583-5314
Junho KimDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0002-8977-2925
Stefan G KoenigSynthetic Molecule Process Chemistry, Genentech Inc, South San Francisco, California 94080, United States.ORCID 0000-0002-1878-614X
Paul J ChirikDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-8473-2898

Funding

Earth abundant catalysts as an enabling tool for organic synthesisR01GM121441 · NIGMS · PRINCETON UNIVERSITY · PI CHIRIK, PAUL J · 2017 to 2025
$2.5M
NIGMS NIH HHS R01 GM121441
6 · The paper itself

Abstract

Experimental and computational studies have been conducted and established the general principles for enabling redox-neutral C-H activation by iron(II) complexes. The idealized octahedral iron(II) dimethyl complex, (depe)

Identifiers

PMID39450764
PMCPMC11583065

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.