Evidence map›Paper›PMID 39450747›Full record

ArticleJournal of the American Heart Association2024

Native Sinus Hemodynamics and Thrombosis in Transcatheter Heart Valve: Effect of Implant Depth and Coronary Flow.

Hyun Jung Koo, Jihun Kang, Do-Yoon Kang, Jung-Min Ahn, Duk-Woo Park, Seung-Jung Park, Joon-Won Kang, Hojin Ha, Dong Hyun Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hyun Jung KooDepartment of Radiology and Research Institute of Radiology, Cardiac Imaging Center University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0001-5640-3835
Jihun KangInterdisciplinary Program in Biohealth-Machinery Convergence Engineering Kangwon National University Chuncheon South Korea.ORCID 0000-0001-5455-6651
Do-Yoon KangDivision of Cardiology University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0002-6307-0562
Jung-Min AhnDivision of Cardiology University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0003-4031-391X
Duk-Woo ParkDivision of Cardiology University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0001-6643-0239
Seung-Jung ParkDivision of Cardiology University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0002-9187-5405
Joon-Won KangDepartment of Radiology and Research Institute of Radiology, Cardiac Imaging Center University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0001-6478-0390
Hojin HaInterdisciplinary Program in Biohealth-Machinery Convergence Engineering Kangwon National University Chuncheon South Korea.ORCID 0000-0001-6476-2889
Dong Hyun YangDepartment of Radiology and Research Institute of Radiology, Cardiac Imaging Center University of Ulsan College of Medicine, Asan Medical Center Seoul South Korea.ORCID 0000-0001-5477-558X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to investigate the hemodynamic and anatomic factors associated with sinus thrombosis following transcatheter aortic valve replacement (TAVR), integrating in vivo patient data analysis and in vitro experiments. METHODS AND

resultsPostprocedural, 4-dimensional, multiphase computed tomography data from 211 patients enrolled in the ADAPT-TAVR (Anticoagulation Versus Dual Antiplatelet Therapy for Prevention of Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement) study were analyzed. The prevalence of native sinus thrombosis was examined in relation to valve type, implant depth, and anatomic features. In vitro experiments used particle image velocimetry to observe changes in sinus flow based on the transcatheter heart valves (23-mm SAPIEN3, Edwards Lifesciences; and 29-mm CoreValve, Medtronic) height and coronary artery flow. Native sinus thrombosis was more common in self-expanding valves (39.1% versus 14.9%,

conclusionsThis study provides insights into the relationship between transcatheter heart valve deployment and native sinus thrombosis, emphasizing the role of anatomic factors in relation to the risk of sinus thrombosis.

Indexed as

Aortic ValveCoronary CirculationHeart Valve ProsthesisHemodynamicsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAnticoagulantsAortic Valve StenosisFemaleHumansMaleMultidetector Computed TomographyPlatelet Aggregation InhibitorsProsthesis DesignRisk FactorsAnticoagulantsPlatelet Aggregation Inhibitorsaortic stenosiscomputed tomographythrombosistranscatheter aortic valve replacement

Identifiers

PMID39450747
PMCPMC11935712

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.