Evidence map›Paper›PMID 39450721›Full record

ArticleJournal of the American Heart Association2024

Procedural Volume and Outcomes After Septal Reduction Therapies in Hypertrophic Obstructive Cardiomyopathy.

Nirav Patel, Naman S Shetty, Mokshad Gaonkar, Abdulla Shahid, Girija P Divekar, Akhil Pampana, Nehal Vekariya, Peng Li, Mustafa I Ahmed, Garima Arora and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Forward Dynamics: Modern Insights into Mitral Systolic Anterior Motion.Journal of cardiovascular development and disease · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nirav PatelDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.
Naman S ShettyDepartment of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital Boston MA.ORCID 0000-0003-3600-126X
Mokshad GaonkarDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.ORCID 0000-0003-0309-6813
Abdulla ShahidDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.
Girija P DivekarDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.
Akhil PampanaDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.ORCID 0000-0002-4167-0540
Nehal VekariyaDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.
Peng LiSchool of Nursing University of Alabama at Birmingham Birmingham AL.ORCID 0000-0002-9026-9999
Mustafa I AhmedDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.ORCID 0000-0003-0885-8645
Garima AroraDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.
Pankaj AroraDivision of Cardiovascular Disease University of Alabama at Birmingham Birmingham AL.ORCID 0000-0003-2420-3550

Funding

MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Natriuretic Peptide-Renin-Angiotensin-Aldosterone System Rhythm Axis and Nocturnal Blood PressureR01HL160982 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Pankaj Arora · 2022 to 2026
$3.7M
Atrial Natriuretic Peptide and Regulation of Cardiometabolic Health: A Genotype-Guided Human Physiological StudyR01HL163081 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Pankaj Arora · 2022 to 2026
$3.7M
The Effects of Neprilysin Inhibition on Cardiometabolic Health in Black IndividualsR01HL163852 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Pankaj Arora · 2022 to 2026
$3.6M
NHLBI NIH HHS R01 HL160982NHLBI NIH HHS R01 HL163081NHLBI NIH HHS R01 HL163852NHLBI NIH HHS T32 HL007457
6 · The paper itself

Abstract

backgroundSeptal myectomy and alcohol septal ablation (ASA) are septal reduction therapies for patients with symptomatic obstructive hypertrophic cardiomyopathy. Operator and hospital volume may influence outcomes, but contemporary data on this relationship are limited. METHODS AND

resultsThis retrospective cohort study used data from the Vizient Clinical Data Base (2016-2022). Patients with undergoing septal myectomy and ASA were identified using

conclusionsLow operator and hospital volumes were associated with worse outcomes for septal reduction therapies, emphasizing the need to refer patients with hypertrophic cardiomyopathy to high-volume centers with experienced operators.

Indexed as

Cardiac Surgical ProceduresCardiomyopathy, HypertrophicHeart SeptumHospital MortalityAblation TechniquesAgedEthanolFemaleHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMiddle AgedPatient ReadmissionRetrospective StudiesRisk FactorsEthanolalcohol septal ablationhypertrophic cardiomyopathyseptal myectomyvolume

Identifiers

PMID39450721
PMCPMC11935656

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.