Evidence map›Paper›PMID 39450115›Full record

ReviewArrhythmia & electrophysiology review2024

Left Bundle Branch Block-associated Cardiomyopathy: A New Approach.

Shunmuga Sundaram Ponnusamy, Pugazhendhi Vijayaraman, Kenneth A Ellenbogen

Abstract readReview
In one paragraph

Review in Arrhythmia & electrophysiology review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Revisiting Secondary Dilative Cardiomyopathy.International journal of molecular sciences · 2025
    Pooled it
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  7. T Wave Oversensing in Left Bundle Branch Optimised CRT.Arrhythmia & electrophysiology review · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shunmuga Sundaram PonnusamyDepartment of Cardiology, Velammal Medical College Madurai, India.
Pugazhendhi VijayaramanGeisinger Heart Institute, Geisinger Commonwealth School of Medicine Wilkes Barre, PA, US.
Kenneth A EllenbogenVirginia Commonwealth University Medical Center Richmond, VA, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left bundle branch block (LBBB) is frequently associated with structural heart disease, and predicts higher rates of morbidity and mortality. In patients with cardiomyopathy (ejection fraction <35%) and LBBB, current guidelines recommend cardiac resynchronisation therapy (CRT) after 3 months of medical therapy. However, studies have suggested that medical therapy alone would be less effective, and the majority of patients would still need CRT at the end of 3 months. Conversely, CRT trials have shown better results and favourable clinical outcomes in patients with LBBB. In the absence of any other known aetiology, LBBB-associated cardiomyopathy represents a potentially reversible form of cardiomyopathy, with the majority of the patients having reverse remodelling after CRT by left bundle branch pacing. This review provides the mechanism, published evidence and role of conduction system pacing for patients with LBBB-associated cardiomyopathy.

Indexed as

late gadolinium enhancementLeft bundle branch blockleft bundle branch block-associated cardiomyopathyleft bundle branch block-induced cardiomyopathyleft bundle branch pacing

Identifiers

PMID39450115
PMCPMC11499974

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.