Evidence map›Paper›PMID 39449968›Full record

ArticleFrontiers in pharmacology2024

Zhachong Shisanwei pill drug-containing serum protects H

Hanqiong Hu, Yifan Sun, Zhen Yang, Limuge Che, Mingyang Cai, Xiaoxuan Li, Xianju Huang, Hurile Bagen, Wulan Qiqige, Wuyunsiri Guleng and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hanqiong Hu *College of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Yifan Sun *College of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Zhen YangCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Limuge CheMedicine Innovation Center for Nationalities, Inner Mongolia Medical University, Hohhot, China.
Mingyang CaiHospital of Pediatrics, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Xiaoxuan LiCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xianju HuangCollege of Pharmaceutical Science, South-Central Minzu University, Wuhan, China.
Hurile BagenMongolian Medical College, Inner Mongolia Medical University, Hohhot, China.
Wulan QiqigeMongolian Medical College, Inner Mongolia Medical University, Hohhot, China.
Wuyunsiri GulengPsychosomatic Medicine Department, Inner Mongolia International Mongolian Hospital, Hohhot, China.
Liqun MaCollege of Pharmaceutical Science, South-Central Minzu University, Wuhan, China.
Haiying TongCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Zhachong Shisanwei Pill (ZSP) is a classical Mongolian formula that combines 13 types of Chinese medicinal materials and has been used for treating ischemic stroke (IS) for centuries. However, the underlying molecular mechanisms have yet to be fully elucidated. The aim of this study is to explore potential mechanism of ZSP on nerve cells in cerebral ischemic injury. Methods: To simulate the pathological process of oxidative stress following IS, an injury model using PC12 cells was induced with hydrogen peroxide (H Results: Our findings indicate that ZSP medicated serum preconditioning improves the condition of PC12 cells injured by H Discussion: Mongolian medicine ZSP demonstrates protective effects against H

Indexed as

ischemic stroke (IS)MAPK pathwayoxidative stressPC12 cellsZhachong shisanwei pill (ZSP)

Identifiers

PMID39449968
PMCPMC11500078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.