Evidence map›Paper›PMID 39449962›Full record

ArticleCanadian journal of kidney health and disease2024

An Exercise and Wellness Behavior Change Program for Solid Organ Transplant: A Clinical Research Protocol for the Transplant Wellness Program.

Jenna A P Sim, Maneka A Perinpanayagam, Vanessa Bahry, Kathryn Wytsma-Fisher, Kelly W Burak, Debra L Isaac, Stefan Mustata, S Nicole Culos-Reed

Registry-linked trialAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06367244 (Exercise and Wellness Behaviour Change for Solid Organ Transplant), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06367244 narecruitingnot on this map

Exercise and Wellness Behaviour Change for Solid Organ Transplant: A Hybrid Effectiveness-Implementation Trial of the Transplant Wellness Program

TypeinterventionalSponsorUniversity of CalgaryRan2023 to 2033Enrolled420ConditionsTransplantationArmsTransplant Wellness Program - Kidney and Liver
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jenna A P SimFaculty of Kinesiology, University of Calgary, AB, Canada.ORCID https://orcid.org/0000-0001-8035-691X
Maneka A PerinpanayagamDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
Vanessa BahryDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
Kathryn Wytsma-FisherDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.ORCID https://orcid.org/0000-0002-7823-542X
Kelly W BurakDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
Debra L IsaacDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
Stefan MustataDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.
S Nicole Culos-ReedFaculty of Kinesiology, University of Calgary, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Exercise prehabilitation is an evidence-based, safe, and effective method to increase quality of life, physical fitness and function, and post-surgical outcomes in solid organ transplant (SOT) patients. However, few prehabilitation programs for SOT patients exist in practice. Furthermore, there is a lack of multimodal prehabilitation programs that include behavior change support. To address this need, the Transplant Wellness Program (TWP) was designed. Objectives: The objective of the TWP is to assess both the effectiveness and implementation of a comprehensive and multimodal exercise and wellness behavior change intervention for patients undergoing kidney or liver transplant. Design: The TWP is a hybrid effectiveness-implementation trial consisting of exercise and wellness behavior change support. Patients: Individuals who are in evaluation or listed for kidney or liver transplant in Southern Alberta, Canada. Measurements: The primary outcomes of self-reported exercise and quality of life are assessed at intake, post-exercise intervention, 6 months post-intake, 12 weeks post-transplant, and annually for 5 years after program completion. Functional fitness measures will be assessed at intake, post-exercise intervention, 12 weeks post-transplant, 6 months post-intake, and 1-year post-intake. The reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework is used to determine the impact of TWP at the individual and health care system level. Methods: Recruitment began in November 2023 and will continue until November 2028. Participants take part in a 12-week exercise intervention and are offered individualized and group behavior change support. Continued exercise support is offered through maintenance classes after the completion of the 12-week intervention. Limitations: The design of the hybrid effectiveness-implementation trial with a single experimental group will not allow for comparisons to a control or usual care group, potentially impacting internal validity. Differences in number of participants between organ groups (kidney vs liver) and cohorts (pre-transplant vs post-transplant) will likely be uneven, requiring consideration when running and interpreting analyses. Conclusions: The TWP aims to support patients throughout the transplant journey through a multimodal and comprehensive exercise and wellness behavior change program. Results from this study will determine the effectiveness of the program and inform future scale-up and sustainability. Trial registry number: NCT06367244.

Indexed as

behavior changeexerciseimplementationprehabilitationSolid organ transplant

Identifiers

PMID39449962
PMCPMC11500225

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.