Evidence map›Paper›PMID 39449943›Full record

ArticleCureus2024

Correlation of Serum Electrolyte Imbalances With Diabetic Duration and Medication Use: A Cross-Sectional Comparative Study.

Bhagwant G Pawar, Madhavi Eerike, Anand K Pyati, Sakthivadivel Varatharajan, Kalpana Mali, Venu Gopala R Konda

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Bhagwant G PawarPharmacology, All India Institute of Medical Sciences, Bibinagar, IND.
Madhavi EerikePharmacology, All India Institute of Medical Sciences, Bibinagar, IND.
Anand K PyatiBiochemistry, All India Institute of Medical Sciences, Bibinagar, IND.
Sakthivadivel VaratharajanInternal Medicine, All India Institute of Medical Sciences, Bibinagar, IND.
Kalpana MaliPharmacology, All India Institute of Medical Sciences, Bibinagar, IND.
Venu Gopala R KondaPharmacology, Neelima Institute of Medical Sciences, Anurag University, Hyderabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCertain anti-diabetic medications may exacerbate electrolyte imbalances, potentially complicating glycemic control in diabetic patients. The present study aimed to correlate the serum electrolyte imbalances such as Na

methodIn this cross-sectional study, 31 patients with type 2 diabetes mellitus (T2DM) and 30 healthy controls, with mean ages of 52.06 and 48.5 years, respectively, were recruited based on eligibility criteria. Data on demographic information, medication history, and duration of diabetes were collected. Fasting blood sugar (FBS), postprandial blood sugar (PPBS), glycated hemoglobin (HbA1C), and serum electrolytes were measured. The data were statistically analyzed. The mean differences in serum electrolytes between T2DM patients and non-diabetic participants were compared using the Mann-Whitney U test, and correlation analysis was performed. A p-value of <0.05 was considered statistically significant.

resultAround 9.6% of participants had diabetes duration of less than one year, while the majority (45%) fell within the 1-5-year duration range. Most diabetic patients (61.2%) exhibited poor glycemic control. Statistically significant differences were observed between the mean FBS, PPBS, and HbA1C levels of T2DM (150, 249, and 8.82, respectively) and control group (95, 114, and 5.52, respectively). Analysis of serum electrolytes showed statistically significant differences with regard to Na

conclusionThe study reveals significant electrolyte imbalances in patients with T2DM, characterized by reduced sodium and chloride levels and elevated potassium levels compared to healthy controls. These alterations are closely associated with poor glycemic control and longer disease duration, emphasizing the importance of regular electrolyte monitoring in T2DM management to mitigate potential complications.

Indexed as

anti-diabetic drugsserum chlorideserum electrolytesserum sodiumtype 2 diabetes

Identifiers

PMID39449943
PMCPMC11501493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.