ArticleCureus2024
Efficacy of Intra-articular Super-dose Platelet-Rich Plasma Injection in Improving Pain in a Middle-Aged Sedentary Female With Meniscal Tear: A Case Report.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Short-term outcomes of two PRP-based treatment protocols for Stoller grade I-II meniscal lesions: serial ultrasound-guided perimeniscal PRP injections versus arthroscopic management with a single intra-operative intra-articular PRP injection.BMC musculoskeletal disorders · 2026Article
- Potential sources of pain in symptomatic degenerative meniscal tear: A narrative review.Osteoarthritis and cartilage open · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case study explores the use of super-dose platelet-rich plasma (PRP) in managing a meniscal tear in a 43-year-old woman with left knee pain. The patient was diagnosed with a vertical longitudinal tear of the body and posterior horn medial meniscus, confirmed through magnetic resonance imaging. Super-dose PRP, characterized by a higher platelet volume (8 ml), was administered intra-articular. Post-injection, the patient reported initial discomfort for a few days, but significant improvements in pain and range of motion (ROM) were observed within the first week. Over 12 weeks, her visual analog scale pain score decreased from 8/10 during activity to 2/10, and her ROM returned to full functionality. The case supports the hypothesis that super-dose PRP may enhance the healing process in meniscal injuries by promoting tissue healing and regeneration through the release of growth factors, angiogenesis, collagen synthesis, and inflammation modulation. This case highlights PRP's potential as a non-surgical treatment for meniscal tears. Further large-scale studies and randomized controlled trials are needed to validate these results, optimize dosing strategies, and determine which patient populations will benefit most from this innovative treatment approach.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.