Evidence map›Paper›PMID 39449768›Full record

ArticleJournal of fluorine chemistry2023

Recent advances in the strategic incorporation of fluorine into new-generation taxoid anticancer agents.

Kalani Jayanetti, Kathryn Takemura, Hersh Bendale, Ashna Garg, Iwao Ojima

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fluorine chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kalani JayanettiDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.
Kathryn TakemuraDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.
Hersh BendaleDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.
Ashna GargDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.
Iwao OjimaDepartment of Chemistry, Stony Brook University, Stony Brook, NY 11794-3400, USA.

Funding

Development of the Next Generation of FABP5 Inhibitors to Treat Prostate CancerR01CA237154 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI KACZOCHA, MARTIN, OJIMA, IWAO · 2020 to 2024
$3.3M
Tumor -Targeting Chemotherapeutic AgentsR01CA103314 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI OJIMA, IWAO · 2003 to 2013
$3.1M
NCI NIH HHS R01 CA103314NCI NIH HHS R01 CA237154
6 · The paper itself

Abstract

This account describes our recent progress on the strategic incorporation of fluorine and organofluorine moieties into new-generation taxoid anticancer agents for medicinal chemistry and chemical biology studies. In the case study 1, novel 3rd-generation fluorotaxoids bearing 3-OCF

Indexed as

DifluorovinyltaxoidFluorine-containingMolecular docking analysisStructure-activity relationshipTaxane

Identifiers

PMID39449768
PMCPMC11500632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.