ArticleFrontiers in chemistry2024
Magnetic gelatin-hesperidin microrobots promote proliferation and migration of dermal fibroblasts.
Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Magnetic Microrobots for Drug Delivery: A Review of Fabrication Materials, Structure Designs and Drug Delivery Strategies.Molecules (Basel, Switzerland) · 2025Review
- Skin Photoaging and the Biological Mechanism of the Protective Effects of Hesperidin and Derived Molecules.Antioxidants (Basel, Switzerland) · 2025Review
- Micro/Nanorobots in Wound Healing: Bridging the Gap from Concept to Clinical Translation.International journal of nanomedicine · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermal fibroblasts play a crucial role in the formation of granulation tissue in skin wounds. Consequently, the differentiation, migration, and proliferation of dermal fibroblasts are considered key factors in the skin wound healing process. However, in patients with diabetic foot ulcers, the proliferation and migration of fibroblasts are impaired by reactive oxygen species and inflammatory factors impair. Therefore, a novel magnetic gelatin-hesperidin microrobots drug delivery system was developed using microfluidics. The morphology, motility characteristics, and drug release of the microrobot were assessed, along with its impact on the proliferation and migration of human dermal fibroblasts under high-glucose conditions. Subjected to a rotating magnetic field, the microrobots exhibit precise, controllable, and flexible autonomous motion, achieving a maximum speed of 9.237 μm/s.
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Registered trials
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