Evidence map›Paper›PMID 39449571›Full record

ArticleExperimental physiology2025

Effect of prolonged sitting on dynamic cerebral autoregulation in the anterior and posterior cerebral circulations.

Shotaro Saito, Hayato Tsukamoto, Marino Karaki, Narumi Kunimatsu, Shigehiko Ogoh

Abstract read
In one paragraph

Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shotaro SaitoDepartment of Biomedical Engineering, Toyo University, Saitama, Japan.ORCID 0000-0003-1133-0091
Hayato TsukamotoFaculty of Sport Sciences, Waseda University, Saitama, Japan.ORCID 0000-0001-5512-0497
Marino KarakiGraduate School of Health and Sport Sciences, hukyo University, Aichi, Japan.
Narumi KunimatsuDepartment of Biomedical Engineering, Toyo University, Saitama, Japan.
Shigehiko OgohDepartment of Biomedical Engineering, Toyo University, Saitama, Japan.ORCID 0000-0001-5297-6468

Funding

Grant-in-Aid for Scientific Research 22H003470Japanese Ministry of Education, Culture, Sports, Science and TechnologyJST SPRING JPMJSP2159
6 · The paper itself

Abstract

Individuals who experience prolonged sitting daily are reported to be at risk of developing cerebrovascular disease, which is associated, in part, with attenuation in cerebral blood flow regulation. However, the effect of prolonged sitting on dynamic cerebral autoregulation (dCA), a crucial mechanism of cerebral blood flow regulation, remains unclear. Additionally, cerebrovascular disease occurs heterogeneously within cerebral arteries. The purpose of the present study was to examine the hypothesis that prolonged sitting attenuates dCA in the cerebral circulation heterogeneously. Twelve young, healthy participants were instructed to maintain a seated position for 4 h without moving their lower limbs. Mean arterial pressure and mean blood velocities of the middle cerebral artery (MCA V

Indexed as

Cerebrovascular CirculationHomeostasisMiddle Cerebral ArteryPosterior Cerebral ArterySitting PositionAdultArterial PressureBlood Flow VelocityBlood PressureFemaleHumansMaleYoung Adultcerebral blood flow velocitymiddle cerebral arteryposterior cerebral arterysedentarytransfer function analysis

Identifiers

PMID39449571
PMCPMC11689123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.