Evidence map›Paper›PMID 39449544›Full record

ArticleAdvanced healthcare materials2025

Platelet Extracellular Vesicles Loaded Gelatine Hydrogels for Wound Care.

Florence Back, Alexandre Barras, Ariunjargal Nyam-Erdene, Jen-Chang Yang, Sorin Melinte, José Rumipamba, Thierry Burnouf, Rabah Boukherroub, Sabine Szunerits, Er-Yuan Chuang

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Florence BackUniversité de Lille, CNRS, Université Polytechnique Hauts-de-France, UMR 8520 - IEMN, Lille, F-59000, France.
Alexandre BarrasUniversité de Lille, CNRS, Université Polytechnique Hauts-de-France, UMR 8520 - IEMN, Lille, F-59000, France.
Ariunjargal Nyam-ErdeneInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, 23561, Taiwan.
Jen-Chang YangInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, 23561, Taiwan.
Sorin MelinteUniversité catholique de Louvain, ICTEAM, Louvain-la-Neuve, 1348, Belgium.
José RumipambaUniversité catholique de Louvain, ICTEAM, Louvain-la-Neuve, 1348, Belgium.
Thierry BurnoufInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, 23561, Taiwan.
Rabah BoukherroubUniversité de Lille, CNRS, Université Polytechnique Hauts-de-France, UMR 8520 - IEMN, Lille, F-59000, France.
Sabine SzuneritsUniversité de Lille, CNRS, Université Polytechnique Hauts-de-France, UMR 8520 - IEMN, Lille, F-59000, France.ORCID 0000-0002-1567-4943
Er-Yuan ChuangInternational Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Shuang-Ho Campus, New Taipei City, 23561, Taiwan.

Funding

French Renatech network, Belgian F.R.S - FNRS: R.8008.21, EuroNanomed III-GSkin ANR-21-ENM3-0002National Science and Technology Council (NSTC) 112-2221-E-038-002-MY3National Science and Technology Council (NSTC) 112-2622-E-038-006National Science and Technology Council (NSTC) 113-2923-E-038 -001-
6 · The paper itself

Abstract

Platelet extracellular vesicles (pEVs) isolated from clinical-grade human platelet concentrates are attracting attention as a promising agent for wound healing therapies. Although pEVs have shown potential for skin regeneration, their incorporation into wound bandages has remained limitedly explored. Herein, gelatine-based hydrogel (PAH-G) foams for pEVs loading and release are formulated by crosslinking gelatine with poly(allylamine) hydrochloride (PAH) in the presence of glutaraldehyde and sodium bicarbonate. The optimized PAH-G hydrogel foam, PAH

Indexed as

Blood PlateletsExtracellular VesiclesGelatinHydrogelsWound HealingAnimalsHumansMaleMicePolyaminesRatsRats, Sprague-DawleySkinGelatinHydrogelsPolyamineschronic woundshydrogel foamplatelet extracellular vesiclesskin regenerationwound model

Identifiers

PMID39449544
PMCPMC11694086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.