Evidence map›Paper›PMID 39449422›Full record

ArticleJournal of xenobiotics2024

Altered Expression of Thyroid- and Calcium Ion Channels-Related Genes in Rat Testes by Short-Term Exposure to Commercial Herbicides Paraquat or 2,4-D.

Enoch Luis, Vanessa Conde-Maldonado, Edelmira García-Nieto, Libertad Juárez-Santacruz, Mayvi Alvarado, Arely Anaya-Hernández

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Enoch LuisInvestigadores por México CONAHCYT-Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Circuito Exterior s/n, C.U., Ciudad de México 04510, Mexico.ORCID 0000-0001-8522-190X
Vanessa Conde-MaldonadoMaestría en Ciencias en Sistemas del Ambiente, Centro de Investigación en Genética y Ambiente, Universidad Autónoma de Tlaxcala, Tlaxcala de Xicohténcatl 90000, Mexico.
Edelmira García-NietoMaestría en Ciencias en Sistemas del Ambiente, Centro de Investigación en Genética y Ambiente, Universidad Autónoma de Tlaxcala, Tlaxcala de Xicohténcatl 90000, Mexico.ORCID 0000-0002-6187-0208
Libertad Juárez-SantacruzMaestría en Ciencias en Sistemas del Ambiente, Centro de Investigación en Genética y Ambiente, Universidad Autónoma de Tlaxcala, Tlaxcala de Xicohténcatl 90000, Mexico.ORCID 0000-0001-9731-6543
Mayvi AlvaradoInstituto de Neuroetología, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico.ORCID 0000-0003-2568-7788
Arely Anaya-HernándezMaestría en Ciencias en Sistemas del Ambiente, Centro de Investigación en Genética y Ambiente, Universidad Autónoma de Tlaxcala, Tlaxcala de Xicohténcatl 90000, Mexico.ORCID 0000-0002-7965-8416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to pesticides such as paraquat and 2,4-dichlorophenoxyacetic acid (2,4-D) has been linked to harmful health effects, including alterations in male reproduction. Both herbicides are widely used in developing countries and have been associated with reproductive alterations, such as disruption of spermatogenesis and steroidogenesis. The thyroid axis and Ca

Indexed as

endocrine disruptorherbicidesmale infertilityreproductive toxicitythyroid disruption

Identifiers

PMID39449422
PMCPMC11503356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.