Evidence map›Paper›PMID 39449408›Full record

Observational studyMedical sciences (Basel, Switzerland)2024

Fractional Exhaled Nitric Oxide (FeNO) in Biomass Smoke-Associated Chronic Obstructive Pulmonary Disease.

Juan Silva-Gallardo, Raúl H Sansores, Alejandra Ramírez-Venegas, Robinson E Robles Hernández, Gustavo I Centeno-Saenz, Rafael J Hernández-Zenteno

Abstract readObservational Study
In one paragraph

Observational study in Medical sciences (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan Silva-GallardoHospital General Regional 25, Mexican Social Security Institute, Mexico City 09100, Mexico.
Raúl H SansoresRespiratory Department, Médica Sur Hospital, Mexico City 14050, Mexico.
Alejandra Ramírez-VenegasTobacco and COPD Research Department, Ismael Cosío Villegas National Institute of Respiratory Diseases, Mexico City 14080, Mexico.
Robinson E Robles HernándezTobacco and COPD Research Department, Ismael Cosío Villegas National Institute of Respiratory Diseases, Mexico City 14080, Mexico.ORCID 0000-0003-3708-7368
Gustavo I Centeno-SaenzTobacco and COPD Research Department, Ismael Cosío Villegas National Institute of Respiratory Diseases, Mexico City 14080, Mexico.ORCID 0009-0004-8019-5238
Rafael J Hernández-ZentenoCOPD and Bronchiectasis Clinic, Ismael Cosío Villegas National Institute of Respiratory Diseases, Mexico City 14080, Mexico.ORCID 0000-0002-8710-160X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a disease characterized by local and systemic inflammation independently of the risk factor; during the exacerbations, such inflammation is accentuated and amplified. A practical inflammatory marker and one with an applicable predictive value in the follow-up has been sought. FeNO has shown an excellent performance in that respect within the context of asthma and has also been studied in tobacco-smoke COPD (COPD-TS). In Biomass-smoke COPD (COPD-BS), this, to our knowledge, has not been evaluated.

objectiveTo measure FeNO levels in patients with COPD-BS and to compare these with those of patients with stable COPD-TS and in healthy controls.

methodsTransversal, observational, descriptive, comparative, and analytical study. A total of 57 patients, including 23 with COPD-BS, 17 with COPD-TS, and 17 healthy control subjects. The measurement of FeNO was carried out on all of these by means of the on-line chemiluminescence technique; the values were expressed in parts per billion (ppb) for their analysis.

resultsIt was observed that the FeNO values were similar between COPD-BS and COPD-TS and were significantly different between the healthy and stable COPD (both groups). No correlation was found between pulmonary function and symptoms with FeNO in any of the groups.

conclusionsThe level of FeNO in stable COPD is found to be increased in a similar manner in COPD-BS and COPD-TS, with a significant difference on comparing it with that of the healthy subjects.

Indexed as

Nitric OxidePulmonary Disease, Chronic ObstructiveAgedBiomarkersBiomassBreath TestsCross-Sectional StudiesExhalationFemaleFractional Exhaled Nitric Oxide TestingHumansMaleMiddle AgedSmokeBiomarkersNitric OxideSmokebiomass COPDFeNOinflammation

Identifiers

PMID39449408
PMCPMC11503285

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.