Combined Epiretinal Proliferation and Internal Limiting Membrane Inverted Flap for the Treatment of Large Macular Holes.

Nikolaos Dervenis, Iordanis Vagiakis, Elena P Papadopoulou, Panagiotis Dervenis, Teresa Sandinha

Abstract readCase Reports

In one paragraph

Article in Vision (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Nikolaos DervenisInstitute of Ageing and Chronic Disease, University of Liverpool, Liverpool L69 7ZX, UK.ORCID 0000-0002-7269-2785

Iordanis VagiakisDepartment of Ophthalmology, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0009-0003-2255-1049

Elena P PapadopoulouDepartment of Ophthalmology, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0002-2001-6371

Panagiotis DervenisColchester Eye Centre, Colchester CO4 5JR, UK.ORCID 0000-0002-9303-2161

Teresa SandinhaSt Paul Eye Unit, Royal Liverpool University Hospital, Liverpool L7 8YA, UK.ORCID 0000-0001-5669-7159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We are presenting a new method for the treatment of large macular holes (MHs) with the use of an inverted flap consisting of both internal limiting membrane (ILM) and epiretinal proliferation (EP). A prospective interventional case series was conducted from September 2021 to January 2023. MH patients with coexistent EP visualized preoperatively in macula optical coherence tomography and with a MHs minimum linear diameter larger than 400 microns underwent standard pars plana vitrectomy with the creation of an inverted petaloid flap (consisting of both ILM and EP) and gas tamponade. Sixteen eyes were included in our case series. MHs closure was successful in all the eyes with a single procedure. The preoperative minimum linear diameter was 707.63 (±164.02 μm), and the preoperative best corrected visual acuity was 1.11 ± 0.52. The postoperative BCVA was 0.51 ± 0.20 (

Indexed as

epiretinal proliferationmacular holemacular surgerypars plana vitrectomy

Identifiers

PMID39449396

DOI10.3390/vision8040063

PMCPMC11503290

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.