Evidence map›Paper›PMID 39449339›Full record

ReviewCurrent medicinal chemistry2025

Potential Mechanisms of COVID-19 Related Nervous System Damage and Effects on Female Fertility.

Chen-Yue Qian, Si-Ning Hu, Hua-Dong Liu, Jing-Jin Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chen-Yue QianThe Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China.
Si-Ning HuKey Laboratories of Education Ministry for Myocardial Ischemia, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Hua-Dong LiuThe Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China.
Jing-Jin LiuThe Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China.

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515111145Major scientific research project of Shenzhen People's Hospital SYWGSJCYJ202301National Natural Science Foundation 82200315Natural Science Foundation of Shenzhen Science and Technology Innovation Commission JCYJ20190806153207263Sanming Project of Medicine in Shenzhen SZSM201412012
6 · The paper itself

Abstract

Signs and symptoms that persist or worsen beyond the "acute COVID-19" stage are referred to as long-COVID. These patients are more likely to suffer from multiple organ failure, readmission, and mortality. According to a recent theory, long-lasting COVID-19 symptoms may be caused by abnormal autonomic nervous system (ANS) activity, such as hypovolemia, brain stem involvement, and autoimmune reactions. Furthermore, COVID-19 can also cause impaired fertility in women, which may also be related to inflammation and immune responses. Currently, few treatments are available for long-COVID symptoms. This article reviews the major effects of COVID-19 on the nervous system and female fertility, as well as offers potential treatment approaches.

Indexed as

COVID-19FertilityInfertility, FemaleNervous System DiseasesAutonomic Nervous SystemFemaleHumansSARS-CoV-2ataxia.central nervous systemCOVID-19fertilityimmune responsepharmacological treatment

Identifiers

PMID39449339
PMCPMC12645119

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.