Evidence map›Paper›PMID 39449187›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2025

Type 2 Immune-Dominant Endotype Is Not Associated With Increased Responsiveness to Dupilumab Treatment in Adult Atopic Dermatitis Patients.

Coco Dekkers, Hidde Smits, Dora Stölzl, Lotte Spekhorst, Edward Knol, Femke van Wijk, Inken Harder, Thomas Werfel, Jochen Schmitt, Andreas Kleinheinz and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Innovations and Emerging Therapies in Atopic Dermatitis Part 1.Current treatment options in allergy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Coco DekkersNational Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-2344-6860
Hidde SmitsCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0009-0008-9621-4797
Dora StölzlDepartment of Dermatology and Allergology, Dermatology University Hospital, Kiel, Germany.ORCID https://orcid.org/0000-0001-7321-7305
Lotte SpekhorstNational Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-7537-765X
Edward KnolNational Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-7368-9820
Femke van WijkCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-8343-1356
Inken HarderDepartment of Dermatology and Allergology, Dermatology University Hospital, Kiel, Germany.ORCID https://orcid.org/0000-0002-3079-0440
Thomas WerfelDepartment of Dermatology and Allergology, Hannover Medical School, Hannover, Germany.
Jochen SchmittCenter for Evidence-Based Healthcare, Medical Faculty and University Hospital Carl Gustav Carus, Dresden, Germany.ORCID https://orcid.org/0000-0003-0264-0960
Andreas KleinheinzClinics for Dermatology, Elbe Klinikum Buxtehude, Buxtehude, Germany.ORCID https://orcid.org/0000-0002-0379-4403
Susanne AbrahamUniversity Allergy Center, Medical Faculty, Carl Gustav Carus, Technical University Dresden, Dresden, Germany.ORCID https://orcid.org/0000-0001-7457-6481
Judith ThijsDepartment of Dermatology, Meander Medical Center Amersfoort, Amersfoort, The Netherlands.ORCID https://orcid.org/0000-0003-2753-5235
Stephan WeidingerDepartment of Dermatology and Allergology, Dermatology University Hospital, Kiel, Germany.ORCID https://orcid.org/0000-0003-3944-252X
Marjolein de Bruin-WellerNational Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-1249-6993
Daphne BakkerNational Expertise Center for Atopic Dermatitis, Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-0193-5794
Julia DrylewiczCenter for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-9434-8459

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39449187
PMCPMC11707302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.