Evidence map›Paper›PMID 39449131›Full record

ReviewBMC immunology2024

A novel approach to immune thrombocytopenia intervention: modulating intestinal homeostasis.

Hui Sun, Lixiang Yan, Lijun Fang, Zhexin Shi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hui Sun *National Clinical Research Centre for Chinese Medicine Acupuncture and Moxibustion, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, China.
Lixiang Yan *National Clinical Research Centre for Chinese Medicine Acupuncture and Moxibustion, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, China.
Lijun FangNational Clinical Research Centre for Chinese Medicine Acupuncture and Moxibustion, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, China.
Zhexin ShiNational Clinical Research Centre for Chinese Medicine Acupuncture and Moxibustion, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, China. shzhx0604@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune thrombocytopenia (ITP) is a prevalent hemorrhage condition that causes notable immune-related abnormalities. Recently discovered data has shown that the intestinal flora plays a crucial role in maintaining a balanced immune system. Furthermore, an imbalance in gut flora has the potential to increase the possibility of developing ITP. Moreover, some studies reported a strong link between inflammatory bowel disease (IBD) and ITP. In this review, we described the significance of gut immunity in ITP. In addition, we explored the associations between gut flora and ITP as well as IBD and ITP. Finally, we examined the effectiveness of existing therapies that regulate gut homeostasis and their impact on the prognosis of patients with ITP.

Indexed as

Gastrointestinal MicrobiomeHomeostasisInflammatory Bowel DiseasesPurpura, Thrombocytopenic, IdiopathicAnimalsHumansIntestinesImmune thrombocytopeniaInflammatory bowel diseaseIntestinal floraIntestinal immunityProbiotics

Identifiers

PMID39449131
PMCPMC11515598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.