Evidence map›Paper›PMID 39449056›Full record

Trial reportAdvances in rheumatology (London, England)2024

A functional exercise program improves pain and health related quality of life in patients with fibromyalgia: a randomized controlled trial.

Giovana Fernandes, Michele Nery, Sandra Mara Meireles, Rebeka Santos, Jamil Natour, Fabio Jennings

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Advances in rheumatology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03682588 nacompletednot on this map

A Functional Exercise Program Improves Pain and Health Related Quality of Life in Patients With Fibromyalgia: A Randomized Controlled Trial

TypeinterventionalSponsorFederal University of São PauloRan2018 to 2020Enrolled82ConditionsFibromyalgiaArmsPhysical activity
NCT07782255 nacompletednot on this mapstarted 2025, after this paper: background citation

Interdisciplinary Therapeutic Intervention for People With Persistent Pain

TypeinterventionalSponsorPlaya Ancha UniversityRan2025 to 2025Enrolled15ConditionsFybromyalgiaArmsMultimodal Interdisciplinary Therapeutic Intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giovana FernandesRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.
Michele NeryRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.
Sandra Mara MeirelesRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.
Rebeka SantosRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.
Jamil NatourRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil. jnatour@unifesp.br.ORCID 0000-0002-4588-9902
Fabio JenningsRheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Botucatu, 740, São Paulo, SP, CEP: 04023-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveFibromyalgia is a non-inflammatory syndrome characterized by generalized muscle pain, with other symptoms. Numerous forms of physical training for this population have been studied through high-quality randomized clinical trials involving strength, flexibility, aerobic conditioning and multicomponent exercise interventions. This research evaluated the effectiveness of a functional exercise program at reducing pain, improving functional capacity, increasing muscle strength as well as improving flexibility, balance and quality of life in individuals with fibromyalgia.

methodsEighty-two women with fibromyalgia were randomized into two groups. The functional exercise group performed functional exercises in 45-minute sessions twice per week for 14 weeks. The stretching exercise group performed flexibility exercises with the same duration and frequency. Outcome measures were: visual analog scale for widespread pain; Fibromyalgia Impact Questionnaire for health-related quality of life; Timed Up and Go test for functional performance; one-repetition maximum for muscle strength, Sit and Reach test on Wells bench for flexibility; Berg Balance Scale for balance; SF-36 for general quality of life.

resultsAfter the intervention, the functional exercise group had a statistically significant reduction in pain (interaction p = 0.002), and improvement in health-related quality of life measured by the Fibromyalgia Impact Questionnaire (interaction p < 0.001) and in general health state domain of SF-36 (interaction p = 0.043) compared to the stretching exercise group. No significant differences between groups were found regarding improvements in functional capacity, muscle strength, flexibility or balance.

conclusionFunctional exercise training was effective at reducing pain and improving quality of life in patients with fibromyalgia compared to stretching exercises.

trial registrationClinicalTrials.gov Identifier: NCT03682588 First prospectively registered in March 2018.

Indexed as

Exercise TherapyFibromyalgiaMuscle StrengthQuality of LifeAdultFemaleHumansMiddle AgedMuscle Stretching ExercisesPain MeasurementPostural BalanceExerciseFibromyalgiaFunctional trainingRehabilitation

Identifiers

PMID39449056
PMCPMC13488760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.