ArticleBMC oral health2024
Effects of clear aligners and traditional removable appliances on oral microbiome in mixed dentition: a comparative study.
Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral Microbiome and Metabolome Changes During Orthodontic Treatments: A Systematic Review of Limited Clinical Evidence.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Assessment of the impact of Z-Spring appliances and clear aligners on salivary parameters and periodontal health in children: a randomized clinical trial.BMC oral health · 2025Trial
- Impact of Z-spring appliance and clear aligner therapy on oral microorganisms in children: A clinical trial.Saudi medical journal · 2025Trial
- Salivary parameters in individuals undergoing orthodontic treatment with clear aligners: a scoping review.Evidence-based dentistry · 2026Article
- Oral microbiota characteristics in children younger than 3 years with febrile seizures: a prospective observational study.BMC microbiology · 2026Observational
- Orthodontic Treatment Need and Short-Term Oral Hygiene Assessment in Children Undergoing Different Early Orthodontic Treatments.Children (Basel, Switzerland) · 2026Article
- Anaerobic stress index to predict microbial ecological shifts in clear aligners.Journal of oral microbiology · 2026Article
- The impact of clear aligners therapy on dental caries: a systematic review.Frontiers in dental medicine · 2026Review
- Duration-Dependent Caries Risk During Clear Aligner Therapy: A Retrospective Analysis.Biomimetics (Basel, Switzerland) · 2025Article
- Biofilm Composition Changes During Orthodontic Clear Aligners Compared to Multibracket Appliances: A Systematic Review.Microorganisms · 2025Review
- Oral health in adolescents: periodontal inflammatory biomarkers during orthodontic clear aligner therapy.Clinical oral investigations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThis prospective study aims to investigate the comparative effects of clear aligners (CA) and traditional removable appliances (RA) on the cariogenic risk of patients in mixed dentition, focusing on the oral microbiome.
methods25 children were included and assigned into CA and RA groups. Supragingival plaque and saliva samples were collected, and clinical parameters including Decay-missing-filled teeth index (DMFT), Plaque Index (PI) and Gorelick Index (GI) were recorded before treatment (T
resultsClinical parameters showed no statistically significant difference between groups at each time point or within group over time (p > 0.05). In both RA and CA groups, saliva exhibited significantly higher alpha diversity compared to supragingival plaque at T
conclusionBoth clear aligners and traditional removable appliances resulted in elevated cariogenic risk of patients in mixed dentition at the microbial level. Distinct alterations in cariogenic species were observed to be induced by various orthodontic appliances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.