Evidence map›Paper›PMID 39448952›Full record

ArticleBMC oral health2024

Silver nanoparticles versus chitosan nanoparticles effects on demineralized enamel.

Mariam Aboayana, Marihan I Elgayar, Mohamed H A Hussein

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariam AboayanaDepartment of Oral Biology, Faculty of Dentistry, Alexandria University, Elmassalah, Alexandria, Egypt. mariam.abdelaziz@alexu.edu.eg.
Marihan I ElgayarDepartment of Conservative Dentistry, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Mohamed H A HusseinDepartment of Conservative Dentistry, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the impacts of different remineralizing agents on demineralized enamel, we focused on chitosan nanoparticles (ChiNPs) and silver nanoparticles (AgNPs).

methodsThis study was conducted on 40 extracted human premolars with artificially induced demineralization using demineralizing solution. Prior to the beginning of the experimental procedures, the samples were preserved in artificial saliva solution. The nanoparticles were characterized by transmission electron microscopy (TEM) and teeth were divided into four equal groups: Group A was utilized as a control group (no demineralization) and received no treatment. Group B was subjected to demineralization with no treatment. Group C was subjected to demineralization and then treated with ChiNPs. Group D was subjected to demineralization and then treated with AgNPs. The teeth were evaluated for microhardness. The enamel surfaces of all the samples were analysed by scanning electron microscopy (SEM) for morphological changes and energy dispersive X-ray analysis (EDX) for elemental analysis.

resultsThe third and fourth groups had the highest mean microhardness and calcium (Ca) and phosphorous (P) contents. SEM of these two groups revealed relative restoration of homogenous remineralized enamel surface architecture with minimal micropores.

conclusionChitosan nanoparticles (NPs) and silver NPs help restore the enamel surface architecture and mineral content. Therefore, chitosan NPs and AgNPs would be beneficial for remineralizing enamel.

Indexed as

ChitosanDental EnamelHardnessMetal NanoparticlesMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionSilverSpectrometry, X-Ray EmissionTooth DemineralizationTooth RemineralizationBicuspidCalciumHumansIn Vitro TechniquesNanoparticlesPhosphorusCalciumChitosanPhosphorusSaliva, ArtificialSilverChitosan nanoparticlesDemineralizationEnamelNoncarious lesionsRemineralizationSilver nanoparticles

Identifiers

PMID39448952
PMCPMC11520134

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.