Evidence map›Paper›PMID 39448811›Full record

ArticleProstate cancer and prostatic diseases2025

Social determinants of health and surgical outcomes of minimally invasive radical prostatectomy: a national population-based study.

Spencer M Mossack, Antonio Franco, Daniel F Roadman, Morgan R Sturgis, Angelo Orsini, Gabriele Bignante, Francesco Lasorsa, Christopher L Coogan, Edward E Cherullo, Cosimo De Nunzio and 1 more

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Article in Prostate cancer and prostatic diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Spencer M Mossack *Department of Urology, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-8536-0985
Antonio Franco *Department of Urology, Rush University Medical Center, Chicago, IL, USA.
Daniel F RoadmanDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.
Morgan R SturgisDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.
Angelo OrsiniDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.ORCID 0009-0009-9372-5847
Gabriele BignanteDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.ORCID 0009-0008-4269-6663
Francesco LasorsaDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-8884-0757
Christopher L CooganDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.
Edward E CherulloDepartment of Urology, Rush University Medical Center, Chicago, IL, USA.
Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, La Sapienza University, Rome, Italy.ORCID 0000-0002-2190-512X
Riccardo AutorinoDepartment of Urology, Rush University Medical Center, Chicago, IL, USA. ricautor@gmail.com.ORCID 0000-0001-7045-7725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocioeconomic determinants of health (SDOH) are often unvalued during surgery risk stratification; hence, they might be a major source of disparity that can jeopardize outcomes related to urological surgery. The aim of our study is to evaluate the impact of SDOH on postoperative outcomes following minimally invasive radical prostatectomy (MIRP).

methodsPatients who underwent MIRP between 2011 and 2021 were retrospectively analyzed by using PearlDiver-Mariner, an all-payer insurance claims database. International Classification of Diseases diagnosis and procedure codes were used to identify patient's characteristics, postoperative complications and SDOH. Outcomes were compared using multivariable regression models.

resultsOverall, 100,035 patients (mean age = 63.24 ± 7.07) underwent MIRP. The 60-day postoperative complication rate was 18%. Approximately 6% of patients reported at least one SDOH at baseline. SDOH were associated with higher odds of 60-day postoperative complications (OR:1.24, 95% CI:1.15-1.34), including urinary tract infection (OR:1.32, 95% CI:1.20-1.45) and acute kidney injury (OR:1.31, 95% CI:1.00-1.39). Postoperative urethral stricture (OR:1.37, 95% CI:0.92-1.98) did not reach statistical significance at multivariable analysis.

conclusionsPatients with SDOH have a significantly higher risk of postoperative complications following MIRP, especially urinary infection and acute kidney injury. These findings are multifactorial and should prompt identifying measures that might help prevent this large-scale phenomenon.

Indexed as

Minimally Invasive Surgical ProceduresPostoperative ComplicationsProstatectomyProstatic NeoplasmsSocial Determinants of HealthAgedHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.