Evidence map›Paper›PMID 39448765›Full record

ArticleScientific reports2024

Biogenic synthesis and physicochemical characterization of metal nanoparticles based on Calotropis procera as promising sustainable materials against skin cancer.

Rana Ahmed El-Fitiany, Afra AlBlooshi, Abdelouahid Samadi, Mohammad Ahmad Khasawneh

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Biogenic ZnO-CuO Nanocomposites Synthesised UsingNanomaterials (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Alchemy in Nature: The Role ofACS applied materials & interfaces · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rana Ahmed El-FitianyDepartment of Chemistry, College of Science, United Arab Emirates University, Sheikh Khalifa Bin Zayed St, Asharij, P.O. Box No. 15551, Al Ain, UAE.ORCID 0000-0002-4477-1873
Afra AlBlooshiDepartment of Chemistry, College of Science, United Arab Emirates University, Sheikh Khalifa Bin Zayed St, Asharij, P.O. Box No. 15551, Al Ain, UAE.ORCID 0000-0002-8565-0111
Abdelouahid SamadiDepartment of Chemistry, College of Science, United Arab Emirates University, Sheikh Khalifa Bin Zayed St, Asharij, P.O. Box No. 15551, Al Ain, UAE.ORCID 0000-0003-1766-4471
Mohammad Ahmad KhasawnehDepartment of Chemistry, College of Science, United Arab Emirates University, Sheikh Khalifa Bin Zayed St, Asharij, P.O. Box No. 15551, Al Ain, UAE. mohammad.khasawneh@uaeu.ac.ae.ORCID 0000-0001-5853-8311

Funding

United Arab Emirates University G00004400
6 · The paper itself

Abstract

The UAE harbors a rich diversity of wild medicinal plants, such as Calotropis procera (CP), that are renowned for their extensive use in traditional medicine due to their abundance of bioactive phytochemicals. Zinc and iron metals possess significant pharmacological effects including antioxidant and anticancer properties. In this study, nanoparticles (NPs) containing zinc and iron were green synthesized utilizing ethanolic and aqueous extracts of CP aerial parts. UV-Vis spectra revealed absorption peaks around 270-275 nm, while FT-IR analysis confirmed successful coating of the NPs with plant's phytochemicals. SEM/EDX analysis indicated a more potent reducing effect of the aqueous extract, whereas the alcoholic extract demonstrated more effective coating of the NPs. DLS showed monodispersed NPs with average sizes of 32.67-202 nm. The alcoholic extract-based zinc and iron NPs exhibited the highest phenolic and flavonoid contents (51.06 ± 2.82 µg of GAE/mg of DW and 66.26 ± 1.12 µg of Qu/mg of DW, respectively) and the strongest antioxidant effect against ABTS and DPPH radicals (IC

Indexed as

AntioxidantsCalotropisMetal NanoparticlesPlant ExtractsCell Line, TumorCell SurvivalGreen Chemistry TechnologyHumansIronSkin NeoplasmsSpectroscopy, Fourier Transform InfraredZincAntioxidantsIronPlant ExtractsZincAntioxidantCalotropis proceraGreen nanoparticlesSkin cancer

Identifiers

PMID39448765
PMCPMC11502920

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.