Evidence map›Paper›PMID 39448764›Full record

ArticleScientific reports2024

Deep learning improves physician accuracy in the comprehensive detection of abnormalities on chest X-rays.

Pamela G Anderson, Hannah Tarder-Stoll, Mehmet Alpaslan, Nora Keathley, David L Levin, Srivas Venkatesh, Elliot Bartel, Serge Sicular, Scott Howell, Robert V Lindsey and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Degenerative cervical myelopathy diagnosis: applicability of artificial intelligence-enhanced modalities in a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  16. Diagnosis of Lung Diseases in the Artificial Intelligence Era.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pamela G AndersonImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA. pami.anderson@imagen.ai.
Hannah Tarder-StollImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Mehmet AlpaslanImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Nora KeathleyImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
David L LevinDepartment of Radiology, Stanford University School of Medicine, 453 Quarry Rd, Palo Alto, CA, 94305, USA.
Srivas VenkateshImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Elliot BartelImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Serge SicularImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Scott HowellImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Robert V LindseyImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.
Rebecca M JonesImagen Technologies, 224 W 35th St Ste 500, New York, NY, 10001, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chest X-rays are the most commonly performed medical imaging exam, yet they are often misinterpreted by physicians. Here, we present an FDA-cleared, artificial intelligence (AI) system which uses a deep learning algorithm to assist physicians in the comprehensive detection and localization of abnormalities on chest X-rays. We trained and tested the AI system on a large dataset, assessed generalizability on publicly available data, and evaluated radiologist and non-radiologist physician accuracy when unaided and aided by the AI system. The AI system accurately detected chest X-ray abnormalities (AUC: 0.976, 95% bootstrap CI: 0.975, 0.976) and generalized to a publicly available dataset (AUC: 0.975, 95% bootstrap CI: 0.971, 0.978). Physicians showed significant improvements in detecting abnormalities on chest X-rays when aided by the AI system compared to when unaided (difference in AUC: 0.101, p < 0.001). Non-radiologist physicians detected abnormalities on chest X-ray exams as accurately as radiologists when aided by the AI system and were faster at evaluating chest X-rays when aided compared to unaided. Together, these results show that the AI system is accurate and reduces physician errors in chest X-ray evaluation, which highlights the potential of AI systems to improve access to fast, high-quality radiograph interpretation.

Indexed as

Deep LearningRadiography, ThoracicAlgorithmsArtificial IntelligenceFemaleHumansMalePhysiciansRadiographic Image Interpretation, Computer-AssistedRadiologists

Identifiers

PMID39448764
PMCPMC11502915

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.