Evidence map›Paper›PMID 39448695›Full record

Trial reportScientific reports2024

Optimizing rehabilitation strategies in Parkinson's disease: a comparison of dual cognitive-walking treadmill training and single treadmill training.

Yen-Po Lin, I-I Lin, Wei-Da Chiou, Hsiu-Chen Chang, Rou-Shayn Chen, Chin-Song Lu, Hsiao-Lung Chan, Ya-Ju Chang

Abstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Effects of a gait training program with the FisiorBMC complementary medicine and therapies · 2026
    Trial
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yen-Po LinDepartment of Medical Education, Chang Gung Memorial Hospital Keelung, Keelung, Taiwan.
I-I LinSchool of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, 259, Wen-Hwa 1st Rd, Kweishan, Taoyuan, Taiwan.
Wei-Da ChiouSchool of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, 259, Wen-Hwa 1st Rd, Kweishan, Taoyuan, Taiwan.
Hsiu-Chen ChangProfessor Lu Neurological Clinic, Taoyuan, Taiwan.
Rou-Shayn ChenDepartment of Neurology, Chang Gung Memorial Hospital Linkou, Taoyuan, Taiwan.
Chin-Song LuProfessor Lu Neurological Clinic, Taoyuan, Taiwan.
Hsiao-Lung ChanNeuroscience Research Center, Chang Gung Memorial Hospital Linkou, Taoyuan, Taiwan.
Ya-Ju ChangSchool of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, 259, Wen-Hwa 1st Rd, Kweishan, Taoyuan, Taiwan. yjchang@mail.cgu.edu.tw.

Funding

Chang Gung Medical Foundation CMRPD1M0231Chang Gung University EMRPD1M0411National Science and Technology Council, Taiwan 111-2314-B-182-035-MY3
6 · The paper itself

Abstract

Dual cognitive-walking treadmill training (DTT), designed to replicate real-life walking conditions, has shown promise effect in individuals with Parkinson's disease (PD). This study aims to compare the effects of DTT versus single treadmill training (STT) on cognitive and walking performance under both single and dual task conditions, as well as on fall, patients' subjective feeling, and quality of life. Sixteen individuals with PD were randomly assigned to DTT or STT group and underwent 8 weeks of training. The DTT group received treadmill training with cognitive loads, while the STT group received treadmill training without cognitive load. Outcome measures included gait parameters (speed, step length) and cognitive performance (reaction time, accuracy, composite score) under both single and dual task conditions. Unified Parkinson's Disease Rating Scale-part III (UPDRS-III), Falls Efficacy Scale (FES), Patient Global Impression of Change (PGIC), and Parkinson's Disease Questionnaire (PDQ-39) were also measured. Both DTT and STT groups showed increased comfortable walking speed and step length. Only the DTT group demonstrated significant improvements in cognitive composite score under both single and dual task conditions, as well as UPDRS-III, FES, and PDQ-39(p < 0.05). DTT can enhance cognitive function without compromising walking ability and also have real-world transferability.

Indexed as

CognitionExercise TherapyParkinson DiseaseWalkingAgedExercise TestFemaleGaitHumansMaleMiddle AgedQuality of LifeTreatment OutcomeCognitive-walking dual taskDual task treadmillGaitParkinson’s diseaseTreadmill training

Identifiers

PMID39448695
PMCPMC11502839

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.